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ProteomicsIntegrated analysis of the anoikis-related signature identifies RAC3 as a novel therapeutic target in hepatocellular carcinoma
Introduction: Anoikis is a form of programmed cell death. Anoikis resistance in hepatocellular carcinoma (HCC) promotes cancer cells shedding from the primary tumor site, thus contributing to survival and distant metastasis. However, the prognostic significance of anoikis-related genes (ARGs) and th...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057450 | Pride
Rac3 Hcc Anoikis 
ProteomicsProteomics of human gastric tissues derived from chronic non-atrophic gastritis (CNAG) and gastric intestinal metaplasia (GIM)
Proteomics of human gastric tissues derived from chronic non-atrophic gastritis (CNAG) and gastric intestinal metaplasia (GIM)
ORGANISM(S): Homo Sapiens 
2025-11-25 | PXD071234 |
ProteomicsThe novels biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Continuous renal replacement therapy (CRRT) is regarded as an adjuvant therapy for critically ill, which removes excess fluids and clear uremic toxins, endotoxins, proteins, and inflammatory mediators...
ORGANISM(S): Homo Sapiens 
2022-03-25 | PXD032807 |
ProteomicsLeucine catabolic enzyme AUH regulates brown fat thermogenesis through HMGylation of PPARγ and RNA-binding function in male mice
A strong association between leucine and obesity has been well established; however, the role of leucine catabolic enzymes in adipose tissue remains largely unknown. Here, we show that knockdown of the leucine catabolic enzyme AU RNA binding methylglutaconyl-CoA hydratase (AUH) in brown adipocytes r...
ORGANISM(S): Mus Musculus 
2026-03-09 | PXD075390 |
ProteomicsInteraction partners with NOP2/Sun RNA methyltransferase 2 (NSUN2) in gallbladder carcinoma
Proteins interacting with NSUN2 in gallbladder carcinoma (NOZ cell line)
ORGANISM(S): Homo Sapiens 
2019-03-20 | PXD013152 |
ProteomicsMetabolomics in pancreatic cancer cells influenced by MTHFD2
Metabolomics of pancreatic cancer cell are modified by metabolic enzyme MTHFD2. SW1990 cells were transfected with MTHFD2 siRNA and control siRNA. Cells were collected for metabolomics analysis.
ORGANISM(S): Homo Sapiens 
2021-02-18 | PXD024228 |
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