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UnknownL-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC3478577 | biostudies-literature
ProteomicsKMT2A-rearranged leukemia proteomics
Activating mutations in kinase/PI3K/RAS signaling pathways are common in acute leukemia with KMT2A rearrangements (KMT2A-R). These mutations are often subclonal and their biological impact remain unclear. Using a retroviral acute myeloid leukemia model, we demonstrate that NRASG12D, FLT3ITD, and FLT...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-02 | PXD008213 | Pride
Leukemia Mouse Tmt 
TranscriptomicsMassively Parallel Sequencing Identifies the MicroRNA Transcriptome of Normal and Malignant Human B cells
Profiling of miRNA transcriptome in Human mature B cells from similar populations Profiling of miRNA transcriptome in Human Normal and Malignant B cells, 8 normal samples corresponding to Naïve, Germinal Center, Plasma and Memory B cells and 23 samples derived from B cell malignancy
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-15229 | biostudies-arrayexpress
UnknownSubmicron Plastic Adsorption by Peat, Accumulation in Sphagnum Mosses and Influence on Bacterial Communities in Peatland Ecosystems.
Not available
S-EPMC9670847 | biostudies-literature
TranscriptomicsGenetic Heterogeneity of DLBCL
Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma in adults. The disease exhibits a striking heterogeneity in gene expression profiles and clinical outcomes, but its genetic causes remain to be fully defined. Through whole genome and exome sequencing, we characterized the gen...
ORGANISM(S): Homo sapiens 
2013-01-23 | E-GEOD-43606 | biostudies-arrayexpress
UnknownEarly detection and staging of chronic liver diseases with a protein MRI contrast agent.
Not available
S-EPMC6820552 | biostudies-literature
ProteomicsQuantitative cellular proteome analysis of Fetal- and Adult-Derived MLL-Rearranged Leukemia
Infant and adult MLL-rearranged (MLLr) leukemia represents a disease with few treatment options and a dismal prognosis. Here, we present an in-depth proteomic characterization of in utero-initiated and adult-onset MLLr leukemia in a mouse model of MLL-ENL-mediated leukemogenesis. We characterize ear...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-02 | PXD042249 | Pride
Adult hematopoietic progenitor Tmtpro Mll-rearranged leukemia Fetal hematopoietic progenitor 
ProteomicsQuantitative secretome analysis of fetal and adult hematopoietic progenitors during leukemia initiation and its response to Fibulin and/or Fibronectin treatment.
We describe the proteomic composition of the secretome of fetal and adult hematopoietic progenitors during MLL-rearranged (MLLr) leukemia initiation as well as the pre-leukemic cells’ secretion response to the treatment with Fibulin (Fbln1) and/or Fibronectin (Fn1) using data-independent acquisition...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-02 | PXD049014 | Pride
Bone marrow Leukemia Secretome Extracellular Fetal liver Data-independent acquisition Hematopoietic progenitors 
ProteomicsSecretome and phosphoproteome analysis of THP-1 and KOPN-8 cells treated with Insulin-like growth factor 2.
We describe the secretome and phosphoproteome of human leukemia cell lines, THP-1 and KOPN-8, treated with Insulin-like growth factor 2 (IGF2) using data-independent acquisition mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-04-02 | PXD049016 | Pride
Leukemia Secretome Extracellular Data-independent acquisition Phosphoproteome Igf2 
ProteomicsQuantitative extracellular proteome analysis of fetal liver and adult bone marrow
We describe the proteomic composition of the extracellular environment of fetal and adult hematopoietic progenitors by data-independent acquisition mass spectrometry analysis.
ORGANISM(S): Mus musculus (Mouse) 
2024-04-02 | PXD042251 | Pride
Tissue interstitial fluid Bone marrow Fetal liver Data-independent acquisition Extracellular 
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