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UnknownTranscriptomic regulation of the hypothalamic-pituitary axis by GnRH immunization in Xizang sheep.
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S-EPMC12927403 | biostudies-literature
ProteomicsProteome of TGF-β1-Induced Human Primary Mesothelial Cells treated with and without BCAT1/2 inhibitor
Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis, primarily driven by TGF-β1-induced mesothelial-to-mesenchymal transition. BCAT1 and BCAT2 are key enzymes in branched-chain amino acid metabolism, yet their specific roles and mechanisms in peritoneal fibrosis remain unc...
ORGANISM(S): Homo Sapiens 
2025-10-23 | PXD069866 |
ProteomicsMass spectrometry data of PBMCs after PBS/SEMA3G treatment
The semaphorins encompass a substantial family of secreted and transmembrane glycoproteins, originally recognized as pivotal factors in guiding axonal growth during the development of neural circuitry. Recent studies have uncovered diverse functions of semaphorins in a wide array of immune responses...
ORGANISM(S): Homo Sapiens 
2024-10-25 | PXD057174 |
ProteomicsFunctional Optic Tract Rewiring via Subtype- and Target-specific Axonal Regeneration and Presynaptic Activity Enhancement
We showed that with genetic manipulation as Pten/Socs3 knockout (KO), CNTF overexpression and Lipin1 knockdown (PSCL), RGCs could regenerate and reinnervate into OPN nuclei after pre-OPN optic tract injury. We then performed single-cell RNA sequencing on OPN-projecting retinal ganglion cells and pro...
ORGANISM(S): Mus Musculus 
2024-05-25 | PXD052573 |
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