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TranscriptomicsProtein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells
Unlike mouse embryonic stem (ES) cells, which are closely related to the inner cell mass, human ES cells appear to be more closely related to the later primitive ectoderm. For example, human ES cells and primitive ectoderm share a common epithelial morphology, growth factor requirements, and the po...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-33180 | biostudies-arrayexpress
ProteomicsComparing the plasma membrane proteins of Nek1+/+ and Nek1Kat2J/Kat2J MEFs
Mass spectrometry data comparing the plasma membrane proteins of Nek1-WT and Nek1-Kat2J MEFs enriched by Pierce™ Cell Surface Protein Isolation Kit.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-06 | PXD027493 | Pride
Nek1 Plasma membrane proteins Retromer 
MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
MetabolomicsMechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 70...

2023-07-24 | MTBLS7808 | MetaboLights
ProteomicsIdentification of ubiquitination sites on the GSTM2 protein
The human GSTM2 protein was enriched, followed by mass spectrometry to identify its ubiquitination sites.
ORGANISM(S): Homo Sapiens 
2025-12-15 | PXD071988 |
ProteomicsQuantitative analysis of phosphoproteome in necroptosis
we conducted a systemic quantitative analysis of phosphoproteome regulated by RIPK1 kinase across a time course from complex I to complex IIb formation during necroptosis of FADD deficient Jurkat cells induced by TNFα
ORGANISM(S): Homo Sapiens 
PXD025313 |
ProteomicsIdentification of TRADD phosphorylation sites
We re-introduced Flag-mTRADD into Tradd-/- MEFs, and identified the phosphorylation sites of TRADD which were induced by TNF and inhibited by TAK1 inhibitor 5Z7 using mass spectrometry. We found that TAK1 could mediate the phosphorylation of multiple sites in TRADD upon TNF stimulation. We next perf...
ORGANISM(S): Homo Sapiens 
PXD056588 |
ProteomicsDistinct functions of RIPK1 ubiquitination in regulating its activation mediated by TNFR1 and TLRs signaling
We identified and quantified ubiquitination sites of WT RIPK1 and K627R mutant in TNF signaling pathway and 293T overexpression system
ORGANISM(S): Homo Sapiens Mus Musculus 
2020-10-23 | PXD022157 |
ProteomicsA DIA-based proteome profiling of  largest preovulatory follicle (F1) of hens
In order to further analyze the mechanism of ovulation frequency difference in chicken, we applied DIA quantitative proteomic approach to analyze F1 samples from continuous laying (CL) and intermittent laying (IL) chicken.
ORGANISM(S): Gallus Gallus 
PXD041276 |
Proteomicspp6 is recruited in TNFalpha induced complex I
We identify pp6 is recruited in complex I induced by TNFalpha.
ORGANISM(S): Mus Musculus 
2021-12-14 | PXD030377 |
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