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TranscriptomicsExpression data from Th2 cell of ECM1 KO mice vs WT mice
CD4+ helper T cells are critical for immunological response. Th2 cells, a subset of CD4+ helper T cells, are responsible for asthma and other immune diseases. We found a Th2 secreted protein, ExtraCellular Matrix protein 1 (ECM1), which is highly induced by classic IL-4 signaling pathway during help...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-19707 | biostudies-arrayexpress
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-10-31 | PXD055972 | Pride
Human Irf3 Axin1 
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-11-01 | PXD055574 | Pride
Human Irf3 Axin1 
UnknownStructural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
Not available
S-EPMC10688377 | biostudies-literature
UnknownDevelopment and validation of a machine learning-based interpretable model for predicting sepsis by complete blood cell parameters.
Not available
S-EPMC11284366 | biostudies-literature
UnknownSalivary protein 7 of the brown planthopper functions as an effector for mediating tricin metabolism in rice plants.
Not available
S-EPMC8881502 | biostudies-literature
UnknownHuman leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result.
Not available
S-EPMC8318637 | biostudies-literature
MetabolomicsGlutamate-mediated metabolic rewiring boosts CpxA/R-OmpF porin and proton motive force to resensitize antibiotic-resistant Escherichia coli to ceftazidime

Ceftazidime (CAZ) is a critically important broad-spectrum antibiotic widely used in clinical practice. However, the rapid emergence of bacterial resistance to CAZ poses a significant challenge in treating infections caused by multidrug-resistant pathogens. In this study, we employed a metabolism...

2026-01-20 | MTBLS13732 | MetaboLights
UnknownFe<sup>0</sup>/PTFE Triboelectric Nanogenerators for Ultrafast Dye and Antibiotic Degradation.
Not available
S-EPMC11966318 | biostudies-literature
UnknownA green deep eutectic solvent-based aqueous two-phase system combined with chemometrics for flavonoids extracting and detecting in honey.
Not available
S-EPMC11566322 | biostudies-literature
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