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This study uncovers the cooperative and opposing effects of CD24 and RCC2 on tumor metastasis. CD24 regulates RCC2 through ubiquitination and degradation, and their interaction influences the β-catenin signaling pathway. RCC2 suppresses tumor metastasis by promoting cytoskeletal reorganization and d...
ORGANISM(S): Homo sapiens (Human) 
2025-07-23 | PXD056404 | Pride
Human tubulin beta class IVa (TUBB4A) is a member of the β-tubulin family. In most normal tissues, expression of TUBB4A is little to none, but it is highly expressed in human prostate cancer. Here we show that high expression levels of TUBB4A are associated with aggressive prostate cancers and poor ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD033359 | Pride
In mammals, the X and Y chromosomes are subject to meiotic sex chromosome inactivation (MSCI) during prophase I in the male germline, but their status thereafter is currently unclear. An abundance of X-linked spermatogenesis genes has spawned the view that the X must be active [1-8]. On the other ha...
ORGANISM(S): Mus musculus 
The leaf lamina joint joins the rice leaf blade and sheath, contributing significantly to the leaf angle trait. A more erect leaf facilitates the penetration of sunlight, enhancing photosynthetic efficiency and occupying less space in dense planting. Genetic screening found a mutant increased leaf a...
ORGANISM(S): Oryza sativa Japonica Group 
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