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ProteomicsBone Morphogenetic Protein 9 Protects against Myocardial Infarction by Improving Lymphatic Drainage Function and Triggering DECR1-Mediated Mitochondrial Bioenergetics
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
ORGANISM(S): Mus Musculus 
PXD051517 |
ProteomicsMi-2β promotes immune evasion in melanoma by activating EZH2 methylation
For identification of Mi-2β-interacting proteins, B16F10 cells (1 × 108) were collected and washed three times with PBS and lysed in lysis buffer on ice for 30 min. Cell lysates were collected and then isolated over night by anti-Mi-2β magnetic agarose beads. The anti-Mi-2β magnetic agarose beads we...
ORGANISM(S): Mus Musculus 
2024-02-18 | PXD049467 |
TranscriptomicsGene expression following myocardial infarction with and without stem cell transplantation
Background: Bone marrow-derived multipotent progenitor cell (MPC) transplantation leads to short term functional and bioenergetic improvement in a porcine model of postinfarction Left Ventricular (LV) remodeling despite a low engraftment rate. However, the long term outcome after MPC transplantation...
ORGANISM(S): Sus scrofa 
2010-04-12 | E-GEOD-14643 | biostudies-arrayexpress
ProteomicsDIA anaylsis for human plasma in MI patitents
A total of 386 patients were enrolled from May 2019 to May 2022 in TEDA International Cardiovascular Hospital, Tianjin, China. This study was approved by Institutional Review Board (IRB) at TEDA International cardiovascular hospital, Tianjin, china, and informed consent was obtained from all patient...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD056463 | Pride
Dia Mi Human plasma 
ProteomicsMMP-9 dependent extracellular protein changes in the left ventriclar infarcts at day 7 post myocardial infarction
Glycopeptides of the LVI tissues of WT and MMP-9 null mice at day-7 post-MI.
ORGANISM(S): Mus musculus (Mouse) 
2018-03-06 | PXD001393 | Pride
Mmp-9 Lv Glycopeptides Myocardial infarction 
TranscriptomicsHarnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis
Cell fate decisions depend on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2u Nucleosome Remodeling and Deacetylase (NuRD) complex is controlled by the Ikaros family of lymphoid-lineage determining proteins. Ikaros, an integral component ...
ORGANISM(S): Mus musculus 
2011-11-13 | E-GEOD-32311 | biostudies-arrayexpress
TranscriptomicsExpression data from the hearts of a mouse model of spontaneous myocardial infarction
Mice with homozygous null mutations in the HDL receptor (SR-BI) and apoE genes (SR-BI KO/apoE double KO (dKO) mice) spontaneously develop occlusive, atherosclerotic coronary artery disease (CAD) and die prematurely (50% mortality at 42 days of age) on standard chow diet feeding. Microarray analysis ...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-49937 | biostudies-arrayexpress
UnknownMI-773, a breaker of the MDM2/p53 axis, exhibits anticancer effects in neuroblastoma via downregulation of INSM1.
Not available
S-EPMC8548782 | biostudies-literature
UnknownDisease and disparity in China: a view from stroke and MI disease.
Not available
S-EPMC6558805 | biostudies-literature
UnknownProgrammed Aptamer Screening, Characterization, and Rapid Detection for α-Conotoxin MI.
Not available
S-EPMC9606946 | biostudies-literature
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