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TranscriptomicsA Whole Transcriptional Linkage Analysis of Gene Co-Regulation in Insecticide Resistant House Flies, Musca domestica
Illumina HiSeq 2000 RNASeq was conducted on the mRNA fraction of three adult female Musca domestica strains. Two strains were the insecticide susceptible strains CS and aabys, which has five distinct recessive morphological markers, one on each of the five autosomes in M. domestica. The third strain...
ORGANISM(S): Musca domestica 
2014-01-02 | E-GEOD-39327 | biostudies-arrayexpress
ProteomicsTransketolase promotes MAFLD by limiting inosine-induced mitochondrial activity (Proteomics)
Metabolic dysfunction-associated fatty liver disease (MAFLD) has a global prevalence of about 25% and no approved therapy. Using metabolomic and proteomic analyses, we identified high expression of hepatic transketolase (TKT), a metabolic enzyme of the pentose phosphate pathway, in human and mouse M...
ORGANISM(S): Homo Sapiens 
2024-02-26 | PXD050130 |
ProteomicsSCN Proteomic Study:electroacupuncture induced circadian control in Suprachiasmatic Nucleus
Recent reports highlight phosphorylation as a major role in the regulation of sleep-wake cycles, to a lesser extent, the phosphoproteome in Suprachiasmatic Nucleus (SCN) is not well understood. We use multiplex tandem mass tag (TMT) - labelling coupled with liquid chromatography-mass spectrometry (L...
ORGANISM(S): Mus Musculus 
PXD029450 |
TranscriptomicsPatch-seq Sequencing of mouse glioma cells
Mouse glioma cells are recorded through patch-seq first, and the cytosol was collected afterwards, and the whole transcriptomic RNA library was reconstructed and sequenced afterwards.
ORGANISM(S): Mus musculus 
2026-05-31 | E-MTAB-17027 | biostudies-arrayexpress
ProteomicsLactylation of Hdac1 regulated by Ldh prevents the pluripotent-to-2C state conversion
Embryonic stem cells (ESCs) were labeled with heavy isotopes, 13C615N4-arginine (Arg10) and 13C614N2-lysine (Lys6), or light isotopes, 12C614N4-arginine (Arg0) and 12C614N2-lysine (Lys0), respectively, for a total of 7 passages to ensure efficient labeling (>97%). The ESCs labeled with heavy isotope...
ORGANISM(S): Mus Musculus 
PXD050051 |
ProteomicsQuantitative proteomics of Pseudomonas protegens Pf-5 treated with pyoluteorin and ΔphlG strain
To acquired insights into the pyoluteorin-mediated physiological process of P. fluorescens, label-free quantitative proteomics was used to compare the expression differences between the whole proteome of Pf-5 with and without pyoluteorin. To further investigate the importance of PhlG in physiologica...
ORGANISM(S): Pseudomonas Protegens Pf-5 
2023-01-09 | PXD039317 |
ProteomicsLyn attenuates cisplatin-induced acute kidney injury by inhibition of RIPK1-mediated apoptosis and necroptosis
Our study revealed that Lyn protects from cisplatin-induced nephrotoxicity by suppressing RIPK1-mediated apoptosis, necroptosis and inflammation.
ORGANISM(S): Mus Musculus 
PXD078460 |
ProteomicsSerum proteomics of T2DM individuals with HFpEF after dapagliflozin treatment by tandem mass spectrometry
A quantitative proteomic profiling by TMT was performed on serum of T2DM individuals with or without dapagliflozin treatment
ORGANISM(S): Homo Sapiens 
2022-10-18 | PXD037538 |
ProteomicsGS2-SUG1 module-mediated control of grain size and weight in rice
SUG1 associates with multiple transcription factors, such as OsBZR1, OsMADS56 and OsSPL13, to control grain size through GA and BR signaling as well as growth pathways.
ORGANISM(S): Oryza Sativa Japonica Group 
PXD052270 |
ProteomicsMolecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules
The production of secondary metabolites is one of the major mechanisms for beneficial rhizobacteria to antagonize plant pathogens. However, simultaneously producing large quantities of different secondary metabolites can pose great metabolic burdens and exerts a significant fitness cost on the produ...
ORGANISM(S): Pseudomonas Fluorescens F113 
2021-04-15 | PXD025403 |
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