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ProteomicsIdentification of N-terminal SUMOylation of mouse cofilin-1 by IP-MS
Small ubiquitin-like modifier (SUMO) typically conjugates to target proteins through isopeptide linkage to the ε-amino group of lysine residues. This posttranslational modification (PTM) plays pivotal roles in modulating protein function. As a key regulator of actin cytoskeleton dynamics, cofilins (...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD038392 | Pride
Mouse Cofilin-1 Ip-ms N-terminal sumoylation 
ProteomicshnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain
We show here that the up-regulation of SUMO1-conjugated protein levels in a CFA-induced inflammatory pain model enhances TRPA1 mRNA stability, ultimately leading to increased expression levels.
ORGANISM(S): Homo Sapiens 
PXD046199 |
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