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TranscriptomicsMapping regulatory elements using signatures of open chromatin in Arabidopsis thaliana
Gene expression is controlled by the complex interaction of transcription factors binding to promoters and other regulatory DNA elements. One common characteristic of the genomic regions associated with regulatory proteins is a pronounced sensitivity to DNase I digestion. We reported genome-wide h...
ORGANISM(S): Arabidopsis thaliana 
2012-07-05 | E-GEOD-34318 | biostudies-arrayexpress
GenomicsThe CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres
Plant and animal centromeres comprise megabases of highly repeated satellite sequences, yet centromere function can be specified epigenetically on single-copy DNA by the presence of nucleosomes containing a centromere-specific variant of histone H3 (cenH3). We determined the positions of cenH3 nucle...
ORGANISM(S): Oryza sativa 
2013-11-06 | E-GEOD-50755 | biostudies-arrayexpress
GenomicsGenome-wide nucleosome positioning is orchestrated by genomic regions associated with DNase I hypersensitivity in rice
Nucleosome positioning dictates the DNA accessibility for regulatory proteins, and thus is critical for gene expression and regulation. It has been well documented that only a subset of nucleosomes are reproducibly positioned (phased) in eukaryotic genomes. The most prominent example of phased nucle...
ORGANISM(S): Oryza sativa 
2014-05-01 | E-GEOD-53027 | biostudies-arrayexpress
MetabolomicsNew aspects characterizing nonobese NAFLD by the analysis of the intestinal flora and metabolites using a mouse model

Nonalcoholic fatty liver disease (NAFLD) is a major public health problem due to the high incidence affecting approximately one-third of the world’s population. NAFLD is usually linked to obesity and excessive weight. A subset of patients with NAFLD express normal or low body mass index; thus, th...

2024-02-27 | MTBLS9365 | MetaboLights
TranscriptomicsTranscriptome of rice seedling and callus based on RNA-seq method
To support our research of epigenomics in rice genome, we conducted massively parallel pyrosequencing of mRNAs (RNA-seq) using rice seedling and callus tissues. We obtained a total of 40.1 M reads from seedling and 29.6 M reads from callus.The RNA-seq data derived from the replicates showed high cor...
ORGANISM(S): Oryza sativa Japonica Group 
2011-11-09 | E-GEOD-33265 | biostudies-arrayexpress
GenomicsGenome-wide mapping of cytosine methylation revealed dynamic DNA methylation patterns associated with rice centromeres
Specification and propagation of the centromeres of eukaryotic chromosomes is determined by epigenetic mechanisms. Unfortunately, the epigenetic characteristics of centromeric DNA and chromatin are difficult to define because the centromeres are composed of highly repetitive DNA sequences in most eu...
ORGANISM(S): Oryza sativa 
2010-04-22 | E-GEOD-21414 | biostudies-arrayexpress
GenomicsChIP-seq to identify the positions of three histone modifications in the rice genome
Gene expression is controlled by the complex interaction of transcription factors binding to promoters and other regulatory DNA elements. One common characteristic of the genomic regions associated with regulatory proteins is a pronounced sensitivity to DNase I digestion. We generated genome-wide ...
ORGANISM(S): Oryza sativa 
2011-11-09 | E-GEOD-26733 | biostudies-arrayexpress
GenomicsDNase I hypersensitive sites in two tissues of rice
Gene expression is controlled by the complex interaction of transcription factors binding to promoters and other regulatory DNA elements. One common characteristic of the genomic regions associated with regulatory proteins is a pronounced sensitivity to DNase I digestion. We generated genome-wide ...
ORGANISM(S): Oryza sativa 
2011-11-09 | E-GEOD-26610 | biostudies-arrayexpress
ProteomicsLC-MS based on TurboID proximity labeling technology: Screening for interacting proteins of AL7 and their differences
TurboID tags were fused to AL7 protein, and adjacent interacting proteins were enriched by biotin. The interacting proteins were identified by mass spectrometry after protein extraction, and the differences of interacting proteins before and after TMV treatment were analyzed
ORGANISM(S): Nicotiana Benthamiana 
2025-02-18 | PXD060894 |
TranscriptomicsEuchromatic histone modifications associated with rice centromeres
The centromere is defined by the presence of a centromere-specific histone H3 variant, CENH3. Establishment and maintenance of the centromeric chromatin (CEN chromatin) is determined by poorly understood epigenetic mechanisms. Interestingly, CEN chromatin in several eukaryotes showed euchromatic c...
ORGANISM(S): Oryza sativa 
2011-11-09 | E-GEOD-29597 | biostudies-arrayexpress
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