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TranscriptomicsThe Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends
Chromosomal double-strand breaks (DSBs) are resected by 5M-bM-^@M-^Y-nucleases to form 3M-bM-^@M-^Y single-strand DNA (ssDNA) substrates for binding by homologous recombination and DNA damage checkpoint proteins. Two redundant pathways of extensive resection were described both in cells and in vitro...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-04 | E-GEOD-38601 | biostudies-arrayexpress
ProteomicsHuman fetal left and right frontal lobes LC-MSMS
Inherent hemispheric asymmetry is significant for cognition, language and other functions. An understanding of normal brain and asymmetry development in the early period will further the knowledge of how different hemispheres prioritize specific functions, which is still unknown. We analysed the dev...
ORGANISM(S): Homo sapiens (Human) 
2022-09-30 | PXD034192 | Pride
Fetal frontal lobe 
UnknownBio-inspired vertebral design for scalable and flexible perovskite solar cells.
Not available
S-EPMC7295992 | biostudies-literature
ProteomicsFOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer
The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity ...
ORGANISM(S): Homo Sapiens 
2022-12-21 | PXD039019 |
ProteomicsUpregulation of protein O-GlcNAcylation levels promotes zebrafish fin regeneration
LC-MS/MS was performed to identify O-GlcNAc-glycoproteins. The results demonstrated that the O-GlcNAc glycoproteins
ORGANISM(S): Danio Rerio 
2025-02-22 | PXD059799 |
ProteomicsA Time-resolved Multi-omic Atlas of the Developing Mouse Liver
Liver organogenesis and development is composed of a series of complex, well-orchestrated events. Identification of key factors and pathways governing liver development will help understand this process and may also provide insights for other physiological and pathological processes including cancer...
ORGANISM(S): Mus Musculus 
2019-06-06 | PXD014144 |
ProteomicsA Time-resolved Multi-omic Atlas of the Developing Mouse Stomach
We collected 3 replicates of whole stomach organs at 15 time points that covered embryonic days (E12.5, E13.5, E14.5, E15.5, E16.5, E17.5, E18.5), postnatal days (D1, D3, D5), and postnatal weeks (W1, W2, W3, W6, W8). The sampling time window covered from the earliest day that stomach sampling is an...
ORGANISM(S): Mus Musculus 
2018-08-06 | PXD010702 |
ProteomicsA region-resolved mucosa proteome of the human stomach
The human gastric mucosa is the most active and functional layer that carries out food digestion and metabolic processes in physiological conditions and also the main origin of carcinogenesis in gastric cancer. Anatomically, the human stomach is divided into 7 regions with physiological functions, b...
ORGANISM(S): Homo Sapiens 
2018-11-26 | PXD011821 |
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