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TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of dendritic cell Transcriptomes during LPS response
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cells in RPMI-...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-69256 | biostudies-arrayexpress
TranscriptomicsSmall RNA Solexa sequencing of mouse CD11c+Ia high and CD11c+Ia low cells
We applied Illumina massively parallel signature sequencing to identify miRNomes in CD11c+Ia high and CD11c+Ia low cells.The miRNomes of these DC subsets will contribute to investigate the significance of miRNAs in DC immunobiology. Examination of miRNome in CD11c+Ia high and CD11c+Ia low cells . Al...
ORGANISM(S): Mus musculus 
2015-06-16 | E-GEOD-51574 | biostudies-arrayexpress
TranscriptomicsRNA Sequencing Analysis of Mouse Bone Marrow Derived Dendritic Cells Transcriptomes During Maturation
Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell maturation. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cell...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-60307 | biostudies-arrayexpress
TranscriptomicsSmall RNA Solexa sequencing of mouse hematopoietic progenitor and dendritic cell samples
We applied Illumina massively parallel signature sequencing to identify miRNomes in hematopoietic stem cells, bone morrow-derived immature DCs, mature DCs, and IL-10 and NO-producing regulatory DCs.The miRNomes of these DC subsets will contribute to investigate the significance of miRNAs in DC immun...
ORGANISM(S): Mus musculus 
2015-06-16 | E-GEOD-45882 | biostudies-arrayexpress
TranscriptomicsGene expression signatures for murine alveolar type II lung epithelial cells after tumor bearing
To determine the influence of primary tumors on pre-metastatic lungs, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of alveolar type II epithelial cells (AT-II) in TLR3 deficient mice (Tlr3-/-) and wide-type (WT) littermates with tu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-76397 | biostudies-arrayexpress
TranscriptomicsSmall RNA Solexa sequencing of human liver samples
We applied small RNA Solexa sequencing technology to identify microRNA expression in human liver samples from surgically removed liver tissues including three normal liver tissues (distal normal liver tissue of liver hemangioma), an hepatitis B virus (HBV)-infected liver, a severe chronic hepatitis ...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-21279 | biostudies-arrayexpress
TranscriptomicsGene expression signatures for primary tumor and tumor-derived exosomes
To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-80678 | biostudies-arrayexpress
ProteomicsIdentification of proteins associated with IFN-γR2 in macrophages
Department of Immunology & Center for Immunotherapy
ORGANISM(S): Mus Musculus 
2018-10-25 | PXD011572 |
MetabolomicsMetabolomic and transcriptomic investigations reveal the responses of cucumber leaves exposed to polystyrene nanoplastics (PSNPs)

The uptake and accumulation of nanoplastics by plants have raised particular concerns. However, molecular mechanisms underlying nanoplastic phytotoxicity are still vague and insufficient. Thus, its potential environmental risks and biosafety are receiving increased attention. In this study, cucum...

2024-09-27 | MTBLS3923 | MetaboLights
GenomicsConversion of gastric epithelia to endoderm progenitors by small molecules [DNA methylation]
Forced expression of transcription factors for lineage reprogramming brings hope to cell-based therapy. However, its application is hampered by risks of potential genetic aberrations and tumorigenicity. Using defined small molecules in presence of gastric stromal cells as feeders, we reprogramed hum...
ORGANISM(S): Homo sapiens 
2016-07-24 | E-GEOD-69705 | biostudies-arrayexpress
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