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ProteomicsDPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate the emergence of 2C-like cells and zygotic transcriptional program
The molecular mechanism controlling the zygotic genome activation (ZGA) in mammals remains poorly understood. The 2C-like cells spontaneously emerging from cultures of mouse embryonic stem cells (ESCs) share some key transcriptional and epigenetic programs with 2-cell stage embryos. By studying the ...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-06 | PXD012925 | Pride
Pias4 dppa2 zga sumoylation 
ProteomicsTrincr1 RNA pull down MS in mESC
Long noncoding RNAs (lncRNAs) have emerged as important components of gene regulatory network in embryonic stem cells (ESCs). However, the function and molecular mechanism of lncRNAs are still largely unknown. Here we identified Trincr1 (TRIM71 interacting long noncoding RNA 1) lncRNA that regulates...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-01 | PXD012493 | Pride
Trincr1 Rna pull down Mesc 
UnknownAcupuncture for migraine prophylaxis: a randomized controlled trial.
Not available
S-EPMC3291669 | biostudies-literature
UnknownThyroid disease and breast cancer, benign breast neoplasm: a two-sample Mendelian randomization study.
Not available
S-EPMC12513146 | biostudies-literature
UnknownAnalysis on Acupoint Selection and Combination for Amyotrophic Lateral Sclerosis Treated with Acupuncture Based on Data Mining.
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S-EPMC9200494 | biostudies-literature
UnknownEfficacy of acupuncture and moxibustion therapy for simple obesity in adults: A meta-analysis of randomized controlled trials.
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S-EPMC9622642 | biostudies-literature
UnknownAcupuncture-related therapies for post-stroke pain management: a scoping review and evidence map.
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S-EPMC12365601 | biostudies-literature
UnknownElevation of effective p53 expression sensitizes wild-type p53 breast cancer cells to CDK7 inhibitor THZ1.
Not available
S-EPMC9442925 | biostudies-literature
UnknownIncompleteness of the circle of Willis affects sleep quality, cognitive function and inflammation in patients with primary hypertension.
Not available
S-EPMC12452657 | biostudies-literature
UnknownRBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex.
Not available
S-EPMC9945352 | biostudies-literature
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