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ProteomicsAtypical U3 snoRNA Suppresses the Process of Pterygia through Modulating 18S Ribosomal RNA Synthesis
Ribosome biosynthesis plays a crucial role in regulating protein translation and is essential for cell growth and development in physiological progress. The progression and recurrence of Pterygia mainly occur due to the abnormal proliferation and migration of stromal Pterygia fibroblasts. Small nucl...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD030801 | Pride
Pterygium U3 snorna 47s rrna 18s rrna 5' ets Ribosome biosynthesis 
ProteomicsNotoginsenoside R1 regulates ischemic myocardial lipid metabolism through activating AKT/mTOR signaling pathway
Radix notoginseng is widely used to treat ischemic heart disease in China and other Asian countries, and notoginsenoside R1 (NGR1) is its characteristic and large-amount ingredient. However, the potential molecular mechanisms of NGR1 improving ischemic heart diseases are unclear. Our results reveale...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-08-12 | PXD032814 | Pride
Notoginsenoside r1  ischemic heart disease  cardioprotection  lipid metabolism  akt/mtor pathway 
ProteomicsProteomic detection of mouse liver
This study aimed to investigate the mechanism of SYT on lipid metabolism and insulin sensitivity in high-fat diet (HFD)-induced obese mice by means of combining lipidomics and proteomics. The obese mice models were developed via HFD feeding for 20 consecutive weeks. Mice in the treatment group were ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD028317 | Pride
Mouse Liver 
ProteomicsScreening of host proteins interacting with African swine fever virus MGF360-9L
To identify the potential host protein binding to African swine fever virus MGF360-9L, the 3 × FLAG tag MGF360-9L plasmid and empty FLAG were transfected into PK-15 cells for co-immunoprecipitation and LC-MS analysis. The cell lysates were immunoprecipitated using anti-FLAG antibody. Immunoprecipita...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD027260 | Pride
African swine fever virus  mgf360-9l  protein interaction  liquid chromatography-mass spectrometry 
UnknownARMH2 is a cytosolic component of CatSper crucial for sperm function.
Not available
S-EPMC12638846 | biostudies-literature
UnknownThe Influence of PSCA Gene Variation on Its Expression and Gastric Adenocarcinoma Susceptibility in the Northwest Chinese Population.
Not available
S-EPMC4463721 | biostudies-literature
ProteomicsProteomic investigations of transcription factors critical in geniposide-mediated suppression of alcoholic steatosis and in overdose induced hepatotoxicity on liver
Geniposide mediated therapeutic effects and overdose-induced hepatotoxicity
ORGANISM(S): Rattus Rattus 
2019-08-12 | PXD014996 |
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