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UnknownWater pressure effect and influence mechanism of coal mechanical property degradation under mine water immersion conditions.
Not available
S-EPMC12700402 | biostudies-literature
UnknownPreparation and Irreversible Inhibition Mechanism Insight into a Recombinant Kunitz Trypsin Inhibitor from Glycine max L. Seeds.
Not available
S-EPMC7320042 | biostudies-literature
ProteomicsChemoproteomics enables identification of coatomer subunit zeta-1 targeted by a small molecule for enterovirus A71 inhibition
Chemoproteomics identitied coatomer subunit zeta-1 as the anti-EV71 target of a marinopyrrole A derivate
ORGANISM(S): Homo Sapiens 
PXD052206 |
ProteomicsDIA quantitative proteomics of CENPM knockdown SW-13 cells
The project aims to detect the differential expression of proteomics in normal SW-13 cells and CENPM knockdown SW-13 cells
ORGANISM(S): Homo Sapiens 
2024-11-19 | PXD058018 |
ProteomicsNovel Peptidomic Analysis Identifies Peptide Clusters with Potential for Disease Diagnosis and Dysregulated Proteolytic Processing
Mass spectrometry-based peptidomics provides a comprehensive approach to delineate the global proteolytic landscape of diseases and to identify potential biomarkers. However, current data analysis methods struggle to distill the peptidomic signatures of diseases. In this study, we conducted a peptid...
ORGANISM(S): Homo Sapiens 
PXD062496 |
ProteomicsAdhesins, which could adhere to the duck embryo cell that belongs to the outer membrane proteins of Riemerella anatipestifer RA-YM strain sequencing by mass spectrometry (LC-MS/MS)
Infectious serositis of ducks caused by Riemerella anatipestifer infection has brought great losses to poultry industry all over the world. Adhesion and invasion were important pathway of the infection of Riemerella anatipestifer. Gram-negative pathogens’ adhesion and invasion of host cells by means...
ORGANISM(S): Riemerella Anatipestifer Ra-ym 
PXD057236 |
ProteomicsImmune response pattern across the asymptomatic, symptomatic and convalescent periods of COVID-19
We present an integrated analysis of urine and serum proteomics and clinical measurements in asymptomatic, mild/moderate, severe and convalescent cases of COVID-19. We identify the pattern of variation of immune response proteins during COVID-19 infection. The immune response is activated in asympto...
ORGANISM(S): Homo Sapiens 
PXD026442 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
ProteomicsLow glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
This project identified the interacting proteins of p53 under glucose starvation in HEK293 cells.
ORGANISM(S): Homo Sapiens 
PXD041361 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
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