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ProteomicsSecretome profiling of Cryptosporidium sporozoites in the initial interaction processes with host epithelial cells
Sporozoites secrete proteins which can help them adhere to/invade host cells during gliding motility on the surface of host cells. Currently, the composition of secreted proteins of C. parvum during adhesion/invasion of host cells is not fully understood. In this study, TMT labeled quantitative prot...
ORGANISM(S): Homo sapiens (Human) Limnobaculum parvum 
2025-11-17 | PXD028969 | Pride
Secrete proteins Cryptospordium Sporozoites 
UnknownImmunological Features and Potential Biomarkers of Systemic Sclerosis-Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis.
Not available
S-EPMC11959098 | biostudies-literature
UnknownCo9S8 nanoparticle-decorated carbon nanofibers as high-performance supercapacitor electrodes.
Not available
S-EPMC9086558 | biostudies-literature
MetabolomicsMetabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
ProteomicsZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation
The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning, with high BMP signal activating ventral-lateral mesoderm markers directly, and low BMP signal inducing neural tissues. The Zinc finger SWIM domain-containing protein 4 (zswim4) is expressed in the dorsal blas...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD035207 | Pride
Zswim4 Bmp Smad1 
TranscriptomicsInducible iPS Cells Support Full-term Development of Tetraploid Blastocyst–Complemented Embryos
Differentiated somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by forced expression of four transcription factors—Oct4, Sox2, Klf4, and c-Myc. However, it remains undetermined whether the reprogrammed iPS cells are fully pluripotent, resembling normal embryonic stem (ES...
ORGANISM(S): Mus musculus 
2010-08-18 | E-GEOD-17004 | biostudies-arrayexpress
UnknownNanocarriers Loaded with Danshensu for Treating Ischemic Stroke by Reducing Oxidative Stress and Glial Overactivation.
Not available
S-EPMC11339989 | biostudies-literature
MetabolomicsA Randomized Controlled Trial of Shengji Ointment Combined with Bromelain in Promoting Healing of Tendon-Exposed Diabetic Foot Wounds: Metabolomics Profiling Analysis

Background: Diabetic foot tendon exposures are prone to infection, necrosis, and prolonged treatment cycles, not only hindering wound healing but potentially leading to amputation and life-threatening complications. Shengji ointment combined with bromelain has demonstrated preliminary efficacy i...

2025-07-14 | MTBLS12713 | MetaboLights
ProteomicsProteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection
Pneumocystis is a life-threatening fungal pathogen frequently causing fatal pneumonia (PCP) in immunocompromised individuals with high mortality. Recently, B cells have been reported to play a crucial role in the pathogenesis of PCP through producing antibodies and activating CD4+ T cell response. E...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-26 | PXD030103 | Pride
Exosomes Mass spectrometry B lymphocytes Pneumocystis pneumonia 
TranscriptomicsTranscription profiling of acute monocytic leukemia (AML-M5) patients with DNMT3A mutations
To understand the pathogenesis of DNMT3A in acute monocytic leukemia (AML-M5), we identified genes that are expressed differently in leukemia cells from AML-M5 patients collected at diagnosis with DNMT3A mutations (6 cases) compared to those without the mutations (4 cases). Differences of expression...
ORGANISM(S): Homo sapiens 
2011-02-12 | E-GEOD-27187 | biostudies-arrayexpress
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