Sort   by:  
 Page size 
GenomicsHistone variants and modification in T-47D cells
To investigate the impact of histone variants and modification on gene regulation, we report high-throughput profiles of six histone markers, H2A.Z, H3K4me2, H3K9me3, H3K27me3, H3K27ac, and H3K36me3, by ChIP-Seq in T-47D breast cancer cells. Libraries were sequenced with the Illumina HiSeq 2000 anal...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-63109 | biostudies-arrayexpress
ProteomicsThe supernatant of the culture medium of adipocytes LC-MSMS
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease without effective medical therapies. Emerging evidences have suggested a crosstalk between adipose tissue and vascular cells and brown adipose tissue is beneficial for cardiovascular health. Nevertheless, whether brown remodeling...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-07 | PXD064197 | Pride
Mus musculus Supernatant Adipocytes Lc-msms 
UnknownRegulation of plant immunity through histone H3 β-hydroxybutyrylation-mediated transcriptional control.
Not available
S-EPMC12271380 | biostudies-literature
ProteomicsStructural mass spectrometry captures residue-resolved comprehensive conformational rearrangements of a G protein-coupled receptor
GPCR structural studies with in-solution spectroscopic approaches have offered distinctive insights into GPCR activation and signaling that highly complement those yielded from structural snapshots by crystallography or cryo-EM. While most current spectroscopic approaches excel at probing structural...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD048942 |
ProteomicsSIRT5 ameliorates cardiac fibrosis via PCK2 de-succinylation–mediated metabolic reprogramming in cardiac fibroblasts
WT and Sirt5-/- CFBs were stimulated with TGF-β1 (10 ng/mL) for 36 hours. Cells were harvested, snap-frozen, and stored at -80℃. The experiment was independently repeated six times at different time points. Cells from each replicate were pooled to yield more than 3 mg of protein per group. Pooled WT...
ORGANISM(S): Mus Musculus 
2025-11-15 | PXD070811 |
ProteomicsProteogenomic Characterization of Skull-base Chordoma
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
2024-07-01 | PXD053550 |
ProteomicsProteogenomics of urothelial bladder cancer progression reveals the distinguished molecular features of different pathological subtypes
We reported a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 448 trace-tumor-samples from 190 urothelial bladder neoplasm patients, covering the whole spectrum of disease stages and grades. DNA damage was a...
ORGANISM(S): Homo Sapiens 
2023-08-02 | PXD043775 |
ProteomicsIntegrated Proteogenomic Characterization across Major Histological Types of Pituitary Neuroendocrine Tumors
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker discovery, the causative molecular mechanisms are far from being fully defined. Therefore, more studies are needed to imp...
ORGANISM(S): Homo Sapiens 
2022-10-17 | PXD031467 |
ProteomicsComprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes
A comprehensive proteomic and genomic analysis of 438 trace tumor samples from 156 duodenal cancers, covering all 8 major histopathology stages of 2 major and 5 rare subtypes in 23 substages via pathological dissection.
ORGANISM(S): Homo Sapiens 
2022-12-16 | PXD038867 |
ProteomicsProteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues
To explore the biological insights into squamous cell carcinoma (SCC) derived from different organs, we reported a deep proteomic analysis of 333 SCCs of 17 organs and 69 adenocarcinomas (ACs) of 7 organs. Proteomic comparison between pan-SCCs and pan-ACs identifies distinguishable pivotal pathways,...
ORGANISM(S): Homo Sapiens 
2022-05-19 | PXD033794 |
Sort   by:  
 Page size