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MetabolomicsLactobacillus plantarum MR1 alleviates high-carbohydrate diet-induced oxidative stress and liver lipid deposition via upregulating uridine synthesis
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
UnknownPolo-like kinase 1 is related with malignant characteristics and inhibits macrophages infiltration in glioma.
Not available
S-EPMC9811677 | biostudies-literature
ProteomicsNuclear factor 90 isoform of vascular smooth muscle cells accelerates diabetic arteriosclerotic calcification by mediating FBXW7-AGER1-AGEs axis
Hyperglycemia accelerates calcification of atherosclerotic plaques in diabetic patients, and the prolonged accumulation of advanced glycation end products (AGEs) induced by hyperglycemia may be closely related to the pathogenesis of aortic calcification. However, the mechanisms underlying this assoc...
ORGANISM(S): Homo Sapiens 
2024-04-02 | PXD048707 |
ProteomicsPrenylated PALM2 Promotes the Migration of Esophageal Squamous Cancer Cells through Activating Ezrin
Proteins containing a CAAX motif at the C-terminus can occur prenylation modification and regulate the localization and activity of a series of key regulatory proteins, including RAS superfamily members, heterotrimeric G proteins, nuclear lamina protein, and several protein kinases and phosphatases....
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040969 |
ProteomicsThe protein interaction of PALM2 in HEK 293T
We identify the protein interaction of PALM2 in HEK 293T. we find that PALM2 can promote the malignant behaviors of esophageal squamous cancer cell (ESCC). Focusing on the mechanism inside, we reveal that PALM2 promotes the migration of esophageal squamous cancer cells through activating it interact...
ORGANISM(S): Homo Sapiens 
2023-03-08 | PXD040700 |
ProteomicsO-glycosylation in fruit development and ripening
O-glycosylation is a critical post-translational modification (PTM) regulating protein function, yet its role in plant transcription factors remains poorly understood.
ORGANISM(S): Solanum Lycopersicum 
2025-12-16 | PXD072030 |
UnknownPrediction of postoperative infection in elderly using deep learning-based analysis: an observational cohort study.
Not available
S-EPMC10014765 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
UnknownWorldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults.
Not available
S-EPMC7615769 | biostudies-literature
UnknownDiminishing benefits of urban living for children and adolescents' growth and development.
Not available
S-EPMC10060164 | biostudies-literature
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