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Circulating biomarkers play important roles in diagnosis of malignant tumors. N-glycosylation is an important post-translation patter and obviously affect biological behaviors of malignant tumor cells. However, the role of N-glycosylation sites in early diagnosis of tumors still remains further inve...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036198 | Pride
Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD053939 | Pride

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
Proteomic analyses of the ocular posterior pole tissues at 6 weeks after induction of form-deprived myopia and lens-induced myopia models in guinea pigs.
ORGANISM(S): Cavia Porcellus 
2022-11-01 | PXD037872 |
A septicemia model was established by intraperitoneal injection of lipopolysaccharide (LPS), followed by tail vein injection of imatinib in the treatment group and normal saline injection in the control group. Flow cytometry was used to detect inflammatory factors, and hematoxylin staining was used ...
ORGANISM(S): Mus Musculus 
2024-02-27 | PXD050204 |
The differences between wild-type mice and target gene knockout mice were analyzed by proteomic tests.
ORGANISM(S): Mus Musculus 
2025-01-13 | PXD059745 |
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