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TranscriptomicsCopy Number Abnormalities in Canine Mammary Cancers
Spontaneously occurring canine mammary cancer (MC) represents an excellent model of human breast cancer, but is greatly understudied. We performed high density arrays on 12 canine MC cases, including 7 simple carcinomas and four complex carcinomas. Simple carcinomas, which histologically match human...
ORGANISM(S): Canis lupus familiaris 
2014-09-07 | E-GEOD-54535 | biostudies-arrayexpress
TranscriptomicsCopy Number Abnormalities in Sporadic Canine Colorectal Cancers
Human colorectal cancer (CRC) is one of the better-understood systems for studying the genetics of cancer initiation and progression. To develop a cross-species comparison strategy for identifying CRC causative gene or genomic alterations, we performed array comparative genomic hybridization (aCGH) ...
ORGANISM(S): Canis lupus familiaris 
2010-05-15 | E-GEOD-19318 | biostudies-arrayexpress
TranscriptomicsNucleosome positioning changes during human embryonic stem cell differentiation.
Nucleosomes are the basic unit of chromatin. Nucleosome positioning (NP) plays a key role in transcriptional regulation and other biological processes. To better understand NP we used MNase-seq to investigate changes that occur as human embryonic stem cells (hESCs) transition to nascent mesoderm and...
ORGANISM(S): Homo sapiens 
2016-05-16 | E-GEOD-45877 | biostudies-arrayexpress
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