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MetabolomicsAberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

OBJECTIVE: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and rena...

2020-10-20 | MTBLS700 | MetaboLights
ProteomicsTransgenic mice with myeloid-specific overexpression of human S100A12
S100A12, a newly discovered member of the S100 family of calcium regulatory proteins, is located within the same gene cluster on chromosome 1q21 as other S100A family members. In humans, S100A12 is mainly secreted by neutrophils and monocytes, but can also be expressed by tissue cells, such as mucos...
ORGANISM(S): Mus <genus> 
2025-01-25 | PXD060232 |
ProteomicsQuantitative proteomics investigation of total protein and acetylated 4D Label free of 18 samples from H9C2 cells
The quantitative investigation of acetylated proteomics was carried out in this project. To ensure high reliability of the results, we filtered the identification data using a criterion of localization probability>0.75. This study identified a total of 9755 acetylation sites located on 3051 proteins...
ORGANISM(S): Rattus Norvegicus 
2023-06-16 | PXD043035 |
ProteomicsLabel-free quantitative proteomics for screening dynamic autophagy-related proteins during nutrient deprivation in MEFs
A Label-free quantitative proteomic profiling was performed on MEFs with or without nutrient starvation.
ORGANISM(S): Mus Musculus 
2022-10-15 | PXD025450 |
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