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ProteomicsIAP-LC-MS/MS to screen non-histone tri-methylation
using a high throughput mass spectrometry method to identify non-histone lysine tri-methylaiton proteins
ORGANISM(S): Homo sapiens (Human) 
2018-11-27 | PXD011657 | Pride
Ms Lysine trimethylaiton 
ProteomicsThe RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquitylation
We established an APEX proximity labeling strategy in coupled with mass spectrometry to identify interacting proteins of RNF214. In this approach, we first fused an engineered ascorbate peroxidase (APEX2) to either N-terminus or C-terminus of RNF214, expressed these two fusion proteins in HLF, an HC...
ORGANISM(S): Homo Sapiens 
2024-02-18 | PXD049453 |
ProteomicsThe proteome of chilli pepper stem during Sclerotium rolfsii Infection
In order to further understand the corresponding mechanism of pepper plants in different infection stages.The blocks of fungal mycelia were inoculated on the soil surface about 2 cm away from the base of stem of the pepper plants at the six-leaf stage. After getting rid of the hyphae on stem surface...
ORGANISM(S): Capsicum Annuum 
PXD029372 |
ProteomicsAutophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma
As a first-line drug for treating advanced hepatocellular carcinoma, the resistance to sorafenib has always attracted attention. However, most attention has been focused on a series of mechanisms related to drug resistance caused after sorafenib treatment. In this study, we used proteomic techniques...
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040371 |
ProteomicsProteomic stratification of prognosis and treatment options for small cell lung cancer
We analyzed surgically resected formalin-fixed, paraffin-embedded (FFPE) SCLC samples by proteomic profiling and stratified SCLC into three subtypes (S-I, S-II, and S-III) with distinct clinical outcomes and chemotherapy responses.
ORGANISM(S): Homo Sapiens 
PXD064316 |
ProteomicsMS assay of proteins after CO-IP with GPNMB antibody in hippocampus area
Three mice were excised at day 7 after pilocarpine treatment to induce abundant GPNMB expression (Figures 1 and 2). Hippocampal proteins were extracted and pulled down by anti-GPNMB immunoprecipitation for mass-spectrometer assay.
ORGANISM(S): Mus Musculus 
PXD066376 |
ProteomicsMouse Testis IP-MS Analysis of TEX44 Interacting Proteins
Through whole-exome sequencing of 800 patients with asthenozoospermia, we identified biallelic TEX44 variants in six individuals, all of whom exhibited defective mitochondrial sheath assembly and impaired sperm motility. Using Tex44 knockout mice, we demonstrated that TEX44 interacts with carnitine ...
ORGANISM(S): Mus Musculus 
2025-02-20 | PXD060989 |
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