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MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
ProteomicsGlyco-CPLL: an integrated method for in-depth and comprehensive N-glycoproteome profiling of human plasma
N-glycoproteins are involved in various biological processes. Certain distinctive glycoforms on specific glycoproteins enhance the specificity and/or sensitivity of cancer diagnosis. Therefore, the characterization of plasma N-glycoproteome is essential for new biomarker discovery. Absence of suitab...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD016428 | Pride
Mass spectrometry  papillary thyroid carcinoma  n-glycoproteomics  combinatorial peptide ligands library 
UnknownAn isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis.
Not available
S-EPMC11614888 | biostudies-literature
UnknownIntegrated transcriptome and plant growth substance profiles to identify the regulatory factors involved in floral sex differentiation in Zanthoxylum armatum DC.
Not available
S-EPMC9479546 | biostudies-literature
UnknownDe novo assembly of a near-complete genome of aquatic vegetable Zizania latifolia in the Yangtze River Basin.
Not available
S-EPMC11655518 | biostudies-literature
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-10-31 | PXD055972 | Pride
Human Irf3 Axin1 
ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral in...
ORGANISM(S): Homo sapiens (Human) 
2024-11-01 | PXD055574 | Pride
Human Irf3 Axin1 
UnknownDe novo transcriptome assembly for the five major organs of Zanthoxylum armatum and the identification of genes involved in terpenoid compound and fatty acid metabolism.
Not available
S-EPMC6986037 | biostudies-literature
MetabolomicsRich organic nitrogen impacts clavulanic acid biosynthesis through the arginine metabolic pathway in Streptomyces clavuligerus F613-1

Clavulanic acid (CA) is the preferred clinical drug for the treatment of infections by β-lactam antibiotic-resistant bacteria. CA is produced by Streptomyces clavuligerus, and although there have been many reports on the effects of carbon and nitrogen sources on CA production, the mechan...

2022-12-08 | MTBLS5744 | MetaboLights
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