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ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
ProteomicsIntegrated proteomic and transcriptomic analyses reveal the roles of Brucella BI-1 in cell division and membrane homeostasis of Brucella suis S2
To explore the role of Brucella BI-1 in Brucella suis S2, we constructed the Brucella BI-1 deletion mutant strain and its complementary strain. We then determined the effect of Brucella BI-1 deletion on the physiological characteristics of Brucella suis S2 and revealed them via integrated transcript...
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2020-11-13 | PXD022537 |
TranscriptomicsGene expression profiling in heterophils with Salmonella enteritidis challenge using a chicken 44K Agilent microarray
To determine the transcriptional response to Salmonella enterica serovar Enteritidis (SE) infection, a newly developed chicken 44K Agilent array was used to analyze total RNA of heterophils from SE-resistant (line A) and SE–susceptible chickens (line B), treated with in vitro infection of SE (I) o...
ORGANISM(S): Gallus gallus 
2010-06-20 | E-GEOD-9416 | biostudies-arrayexpress
UnknownDesign, Synthesis and Antibacterial Evaluation of 3-Substituted Ocotillol-Type Derivatives.
Not available
S-EPMC6321515 | biostudies-literature
UnknownA comparative proteomic analysis reveals a new bi-lobe protein required for bi-lobe duplication and cell division in Trypanosoma brucei.
Not available
S-EPMC2837748 | biostudies-literature
UnknownDeep Learning of Nanopore Sensing Signals Using a Bi-Path Network.
Not available
S-EPMC8482760 | biostudies-literature
UnknownBi-FoRe: an efficient bidirectional knockin strategy to generate pairwise conditional alleles with fluorescent indicators.
Not available
S-EPMC7815861 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownBi/Mn-Doped BiOCl Nanosheets Self-Assembled Microspheres toward Optimized Photocatalytic Performance.
Not available
S-EPMC10490148 | biostudies-literature
ProteomicsBi-directional epithelial-mesenchymal crosstalk provides self-sustaining pro-fibrotic signals in pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is the prototypic progressive fibrotic lung disease with a median survival of 2-4 years. Injury to and/or dysfunction of alveolar epithelium are strongly implicated in IPF disease initiation, but what factors determine why fibrosis progresses rather than normal ti...
ORGANISM(S): Homo sapiens (Human) 
2021-08-19 | PXD025821 | Pride
Tgf-β Ras Secretome Proteomics 
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