Zhou Chan C - OmicsDI

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Unknown (745)
Proteomics (21)
Transcriptomics (8)
Metabolomics (4)
Genomics (3)

Organisms

Homo sapiens (20)
Mus musculus (5)
Rattus norvegicus (3)
Arabidopsis thaliana (1)

Repository

pride (14)
biostudies-arrayexpress (10)
MetaboLights (4)
iProX (3)
MassIVE (3)
EGA (1)
jPOST (1)

Tissue

Cell culture (4)
Epithelial cell (3)
Brain (1)
Conjunctiva (1)
HEK-293T cell (1)
Liver (1)
Plant cell (1)
Umbilical vein endothelium (1)
Vitreous humor (1)

Disease

Alzheimer's disease 1 (1)
Disease free (1)
Dry eye syndrome (1)
Parkinson's disease (1)

Technology Type

Mass Spectrometry (14)
Shotgun proteomics (6)
Mass spectrometry (3)
SWATH MS (3)
Affinity purification coupled with mass spectrometry proteomics (2)
Bottom-up proteomics (2)
Mass spectrometry assay (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
Data-dependent acquisition (1)
Data-independent acquisition (1)
DiaPASEF (1)

Instrument Platform

Illumina NovaSeq 6000 (2)
Orbitrap Eclipse (2)
Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - positive - reverse phase (2)
LTQ Orbitrap Velos (1)
Q Exactive (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - positive - hilic (1)
TripleTOF 5600 (AB Sciex) (1)

Publication Date

2023 (7)
2026 (5)
2015 (4)
2018 (4)
2024 (3)
2022 (3)
2016 (2)
2025 (2)
2013 (1)
2012 (1)
2010 (1)
2008 (1)
2019 (1)

CHEBI ID

CHEBI:17154 (2)
CHEBI:18132 (2)
CHEBI:72959 (2)
CHEBI:73026 (2)
CHEBI:7676 (2)
CHEBI:7916 (2)
CHEBI:100147 (1)
CHEBI:10022 (1)
CHEBI:100241 (1)
CHEBI:10033 (1)
CHEBI:10049 (1)
CHEBI:10070 (1)
CHEBI:10075 (1)
CHEBI:10093 (1)
CHEBI:10100 (1)
CHEBI:10101 (1)
CHEBI:10102 (1)
CHEBI:10112 (1)
CHEBI:10125 (1)
CHEBI:10127 (1)
CHEBI:10136 (1)
CHEBI:10137 (1)
CHEBI:102216 (1)
CHEBI:10222 (1)
CHEBI:102485 (1)
CHEBI:102524 (1)
CHEBI:104011 (1)
CHEBI:10432 (1)
CHEBI:10650 (1)
CHEBI:10698 (1)

Metabolite Name

Pantothenic acid (2)
(+)-Gallocatechin (1)
(+)-Setoclavine (1)
(+/-)-(Z)-2-(5-Tetradecenyl)cyclobutanone (1)
(+/-)-2-Pentylthiazolidine (1)
(+/-)-Fenarimol (1)
(+/-)-Metalaxyl (1)
(+/-)-Naled (1)
(+/-)-Ribaline (1)
(+/-)-threo-Anethole glycol (1)
(-)-4(10)-Thujene (1)
(-)-Aspidospermine (1)
(-)-erythro-Anethole glycol 1-glucoside (1)
(-)-trans-Carveol glucoside (1)
(1R,2R,4S)-p-Menthane-1,2,8-triol 8-glucoside (1)
(2E,4E,6Z)-2,4,6-Decatrienoic acid dehydropiperidide (1)
(2R*,3R*)-1,2,3-Butanetriol (1)
(2S,4S)-Monatin (1)
(3S,5R,6R,6'S)-6,7-Didehydro-5,6-dihydro-3,5,6'-trihydroxy-13,14,20-trinor-3'-oxo-beta,epsilon-caroten-19',11'-olide 3-acetate (1)
(3a,5b)-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl-b-D-Glucopyranosiduronic acid (1)
(3alphaOH,20S,24S)-3,19:20,24-Diepoxydammarane-3,25-diol (1)
(3b,6b,8a,12a)-8,12-Epoxy-7(11)-eremophilene-6,8,12-trimethoxy-3-ol (1)
(3beta,22R,23R,24S)-3,22,23-Trihydroxystigmastan-6-one (1)
(3beta,5alpha,6alpha)-Cholest-8-ene-3,6-diol (1)
(3xi,6E)-1,7-Diphenyl-6-hepten-3-ol (1)
(4Z,9a)-9-(3-Methyl-2-butenoyloxy)-4,10(14)-oplopadien-3-one (1)
(6b,7b,13R)-6,7-Diacetoxy-8,14-labdadiene-13-ol (1)
(7'S,8'S)-4,7'-Epoxy-3,8'-bilign-7-ene-3',5-dimethoxy-4',9,9'-triol 4'-glucoside (1)
(8E,15E)-1,8,15-Heptadecatriene-11,13-diyne (1)
(9S,10S)-9,10-dihydroxyoctadecanoate (1)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (5)
ChIP-seq (2)
Spatial transcriptomics by high-throughput sequencing (1)
Single nucleus RNA sequencing (1)
Methylation profiling by array (1)

Release Date

2025 (107)
2024 (94)
2023 (86)
2022 (78)
2021 (77)
2020 (75)
2018 (64)
2017 (39)
2019 (33)
2016 (27)
2015 (18)
2026 (12)
2013 (9)
2012 (6)
2008 (6)
2011 (6)
2014 (5)
2010 (4)
2009 (4)
2006 (1)
2005 (1)
2004 (1)
2003 (1)
2001 (1)

Lab affiliation

School of Optometry, The Hong Kong Polytechnic University (2)
Associate Professor Developmental and Regenerative Biology School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong (1)
Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong. (1)
Dana Farber Cancer Institute (1)
Denali Therapeutics (1)
Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China (1)
Meng Lab, Department of Basic Research, Guangzhou National Laboratory, No.9, XingDaoHuanBei Road, Guangzhou International Bio-island, Haizhu District Guangzhou, Guangdong, 510005, China (1)
Regeneron Pharmaceuticals, Tarrytown, NY (1)
School of Biological Sciences, The University of Hong Kong (1)
Senior Principal Research Scientist, Head, Ocular Proteomics Platform Singapore Eye Research Institute Singapore (1)
Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China (1)
Singapore Eye Research Institute (1)
The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (1)

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Differential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells

Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...

2022-11-15 | MTBLS2352 | MetaboLights

Thrombopoietin (TPO) protects against heart damage induced by doxorubicin and infarction in rat models

In order to examine the mechanism of TPO on cardiac protection against DOX damage, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against DOX-induced cardiomyopathy Dox and TPO...

ORGANISM(S): Rattus norvegicus

2010-12-29 | E-GEOD-15449 | biostudies-arrayexpress

LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21.

Not available

S-EPMC6078084 | biostudies-literature

SWATH-MS proteomic analysis of nitrogen deficiency response of Arabidopsis

Protein profiling of Arabidopsis thaliana seedling under nitrogen depreciation. Seven days old seedlings of Aradidopsis thaliana were transferred to nitrogen depreciated MS medium for further 48 hours cultivation. Same number of seedlings received same treatment except using MS medium were acted as ...

ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress)

2018-11-21 | PXD007190 | Pride

SRD-1 in AWA neurons is the receptor for female volatile sex pheromones in C. elegans males.

Not available

S-EPMC6399601 | biostudies-literature

A proteome-wide effect of PHF8 knockdown in neuronal activity-dependent synaptic plasticity shows downregulation of Parkinson's disease-associated protein Alpha-synuclein and its interactors

Synaptic dysfunction may underlie the pathophysiology of Parkinson’s disease (PD): a presently incurable condition characterized by motor and cognitive symptoms. Here we used quantitative proteomics to study the role of PHF8, a chromatin-modifying enzyme found to be mutated in intellectual disabilit...

ORGANISM(S): Rattus norvegicus (Rat)

2023-03-10 | PXD036335 | Pride

Synaptic plasticity Neurodegeneracy Proteomics Parkinson's disease Neurodegeneration

Mechanisms of microbial magnetite oxidation by Sideroxydans lithotrophicus ES-1

Iron-oxidizing bacteria are widely found in natural and man-made environments where they influence varied biogeochemical cycles. Despite their prevalence, the mechanisms and Fe(II) substrates used by these organisms remain understudied. To date, there has been limited exploration of the ability of i...

ORGANISM(S): Sideroxydans Lithotrophicus (ncbitaxon:63745)

2024-01-04 | MSV000093770 | MassIVE

Targeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention

Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...

2018-11-26 | MTBLS762 | MetaboLights

Quantitative proteomic analysis of vitreous from patients with proliferative diabetic retinopathy (PDR) using SWATH-MS

Pathological neovascularization and vascular leakage are central drivers of many sight- threatening diseases. While strategies targeting vascular endothelial growth factor (VEGF) have transformed clinical outcomes, a substantial proportion of patients do not benefit from the treatment, partially att...

ORGANISM(S): Homo sapiens (Human)

2026-03-13 | PXD073005 | Pride

Pdr Swath-ms Vitreous proteomics

Thrombopoietin (TPO) protects against heart damage induced infarction in rat model

In order to examine the mechanism of TPO on cardiac protection against myocardial infarction damage (MI), we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against infarction. MI ...