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ProteomicsCD98hc is a target for brain delivery of biotherapeutics
Brain exposure of systemically administered biotherapeutics is highly restricted by the blood-brain barrier (BBB). Here, we report the engineering and characterization of a BBB transport vehicle targeting the CD98 heavy chain (CD98hc or SLC3A2) of heterodimeric amino acid transporters (TV^CD98hc). T...
ORGANISM(S): Homo sapiens (Human) 
2023-07-31 | PXD044159 | Pride
Cns drug delivery Cd98hc Biodistribution Protein engineering Blood-brain barrier 
UnknownTranscriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation.
Not available
S-EPMC6147668 | biostudies-literature
UnknownConstruction of an Emotional Lexicon of Patients With Breast Cancer: Development and Sentiment Analysis.
Not available
S-EPMC10523220 | biostudies-literature
UnknownPopulation structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design.
Not available
S-EPMC2409418 | biostudies-literature
UnknownNF-κB subunits direct kinetically distinct transcriptional cascades in antigen receptor-activated B cells.
Not available
S-EPMC10457194 | biostudies-literature
UnknownStructural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Not available
S-EPMC6726557 | biostudies-literature
UnknownCCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury.
Not available
S-EPMC7259116 | biostudies-literature
UnknownRELT Is Upregulated in Breast Cancer and Induces Death in Breast Cancer Cells.
Not available
S-EPMC11727564 | biostudies-literature
Genomicsena-DATASET-LUDJHU-29-01-2018-17:38:21:660-204 - samples
Sequencing data from 1,005 cancer patients and 812 healthy controls. All samples prepared using Safe-SeqS technology and sequenced on an Illumina MiSeq and/or HiSeq instrument. Paired FASTQ files for correspond to read 1 and the index read present (R and I respectively).
EGAD00001003931 | EGA
GenomicsDetection and localization of surgically resectable cancers with a multi-analyte blood test
Earlier detection is key to reducing cancer deaths. Here we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1,005 patients with clinically detected can...
EGAS00001002764 | EGA
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