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MetabolomicsBeinaglutide modulates abdominal subcutaneous adipose tissue microenvironment and lipid metabolism in diet-induced obese mice: a multi-omics analysis
Beinaglutide (BN), a recombinant human glucagon-like peptide-1 receptor agonist, exhibits beneficial effects on obesity and metabolic disorders; however, its influence on obesity-related adipose tissue alterations and associated molecular changes remains unclear. In this study, C57BL/6J mice underwe...
2026-09-23 | MTBLS15659 | MetaboLights
UnknownOsSCL30 overexpression reduces the tolerance of rice seedlings to low temperature, drought and salt.
Not available
S-EPMC9120446 | biostudies-literature
UnknownSlightly acidic electrolyzed water as an alternative disinfection technique for hatching eggs.
Not available
S-EPMC8749287 | biostudies-literature
GenomicsJmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity
We performed ChIP-seq to chart genome-wide maps of H3K27me3 in brown preadipocytes and mature brown adipocytes. We observed a subset of brown fat-specific genes, but not common fat genes or white fat-specific genes, possess the H3K27me3 mark in preadipocytes, and this mark is erased in mature adipoc...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-55469 | biostudies-arrayexpress
TranscriptomicsJmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity (RNA-Seq)
We performed RNA-Seq for brwon fat, epididymal white fat and soleus muscle of mice to identify brown fat-selective, white fat-selective and common fat genes. RNA-Seq for brown fat, white fat and soleus muscle of wild type C56BL6 mice.
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-56367 | biostudies-arrayexpress
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsTargeted cross-linker delivery for in situ mapping of protein conformations and interactions in mitochondria
Current methods for intracellular protein analysis mostly require the separation of specific organelles or the change of intracellular environment. However, the functions of these proteins are determined by their native microenvironment as they usually form complexes with ions, nucleic acids, and ot...
ORGANISM(S): Homo sapiens (Human) 
2023-05-26 | PXD038658 | Pride
In-cell cross-linking Mitochondria Protein conformations and interactions Nanocarrier delivery Chemical cross-linking mass spectrometry 
ProteomicsTargeted cross-linker delivery for in situ mapping of protein conformations and interactions in mitochondria
Current methods for intracellular protein analysis mostly require the separation of specific organelles or the change of intracellular environment. However, the functions of these proteins are determined by their native microenvironment as they usually form complexes with ions, nucleic acids, and ot...
ORGANISM(S): Homo sapiens (Human) 
2023-05-26 | PXD035433 | Pride
Mitochondria In-situ cross-linking Nanoparticles delivery Protein conformations and interactions Chemical cross-linking mass spectrometry 
ProteomicsProteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed anatoxin-a fumerate.
Characterization of proteome changes to zebrafish and fathead minnow following exposure to the Anatoxin-a surrogate anatoxin-fumerate.
ORGANISM(S): Pimephales Promelas (ncbitaxon:90988) Danio Rerio (ncbitaxon:7955) 
2023-11-29 | MSV000093536 | MassIVE
ProteomicsAnalysis of Nucleocytoplasmic Protein Separation in DPST-Crosslinked Human Neuroblastoma SY5Y Cells
Following DPST crosslinking of human neuroblastoma cells, nuclear-cytoplasmic fractionation was performed using hypotonic lysis to obtain cytoplasmic and nuclear protein compartments. Through systematic analysis of crosslinking mass spectrometry data, we elucidated how subcellular compartmentalized ...
ORGANISM(S): Homo Sapiens 
2025-04-14 | PXD062913 |
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