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TranscriptomicsThrombopoietin (TPO) protects against heart damage induced infarction in rat model
In order to examine the mechanism of TPO on cardiac protection against myocardial infarction damage (MI), we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against infarction. MI ...
ORGANISM(S): Rattus norvegicus 
2012-12-01 | E-GEOD-22489 | biostudies-arrayexpress
ProteomicsBone Morphogenetic Protein 9 Protects against Myocardial Infarction by Improving Lymphatic Drainage Function and Triggering DECR1-Mediated Mitochondrial Bioenergetics
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
ORGANISM(S): Mus Musculus 
PXD051517 |
ProteomicsDIA anaylsis for human plasma in MI patitents
A total of 386 patients were enrolled from May 2019 to May 2022 in TEDA International Cardiovascular Hospital, Tianjin, China. This study was approved by Institutional Review Board (IRB) at TEDA International cardiovascular hospital, Tianjin, china, and informed consent was obtained from all patient...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD056463 | Pride
Dia Mi Human plasma 
ProteomicsMMP-9 dependent extracellular protein changes in the left ventriclar infarcts at day 7 post myocardial infarction
Glycopeptides of the LVI tissues of WT and MMP-9 null mice at day-7 post-MI.
ORGANISM(S): Mus musculus (Mouse) 
2018-03-06 | PXD001393 | Pride
Mmp-9 Lv Glycopeptides Myocardial infarction 
ProteomicsQuantitative proteomics uncovers the regulation of energy metabolism by Shexiang Baoxin Pill in myocardial infarction model rats
Ethnopharmacological relevance: Shexiang Baoxin Pill (SBP) is a traditional formulation of a Chinese patent medicine, which has been commonly used for the treatment of cardiovascular disease (CVD) in China since the 1980s. Previous clinical studies have shown that SBP is safe and effective in patien...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-12-14 | PXD019296 | Pride
Shexiang baoxin pill  cardiovascular disease  lc-ms/ms  quantitative proteomics  energy metabolism 
UnknownExploring cortical excitability in children with cerebral palsy through lower limb robot training based on MI-BCI.
Not available
S-EPMC11986060 | biostudies-literature
TranscriptomicsProgramming and inheritance of parental DNA methylomes in mammals
The reprogramming of parental methylomes is essential for embryonic development. In mammals, paternal 5-methylcytosines (5mCs) have been proposed to be actively converted to oxidized bases. These paternal oxidized bases and maternal 5mCs are believed to be passively diluted by cell divisions. By gen...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-56697 | biostudies-arrayexpress
UnknownExtracellular vesicles derived from different tissues attenuate cardiac dysfunction in murine MI models.
Not available
S-EPMC10655353 | biostudies-literature
TranscriptomicsGenes differentially expressed Haloarcula hispanica strains: PHB (M-NM-^TphaEC mutant) vs 960 (wild type)
Transcriptional profiling of Haloarcula hispanica comparing PHB with 960. PHB represents the PHA synthase genes mutant (i.e., M-NM-^TphaEC) which is deficient in PHBV accumulation when grown in MG medium. 960 represents the wild-type strain which can produce PHBV when grown in MG medium. Goal was to...
ORGANISM(S): Haloarcula hispanica 
2013-01-22 | E-GEOD-42799 | biostudies-arrayexpress
TranscriptomicsGene Expression in Transformed Lymphocytes Reveals Phenotype-Modifying Pathways in Cystic Fibrosis
Heritable genetic variants modify cystic fibrosis (CF) clinical phenotypes, e.g., lung disease, age-of-onset of persistent Pseudomonas aeruginosa (P. aeruginosa), and meconium ileus (MI).  Previous genome wide association studies (GWAS) have begun to inform the genetic architecture of CF phenotypes...
ORGANISM(S): Homo sapiens 
2016-05-19 | E-GEOD-60690 | biostudies-arrayexpress
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