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TranscriptomicsDGE analysis of transcriptome change during photoperiodic regulation of potato tuber formation
We analyzed the transcriptome change during photoperiodic regulation of potato tuber formation 3 samples from longday condition and 2 samples from shortday condition were sequenced
ORGANISM(S): Solanum tuberosum 
2014-03-20 | E-GEOD-45008 | biostudies-arrayexpress
TranscriptomicsDifferent expression patterns in leukemia cells caused by decreased expression of TNF-α
To design an effective antibody therapy to improve clinical outcomes in leukemia, the identification of novel cell surface antigens is needed. Herein, we demonstrate a role for transmembrane tumor necrosis factor-αin leukemia. To characterize tmTNF-α expression in acute leukemia, normal hematopoieti...
ORGANISM(S): Homo sapiens 
2015-07-29 | E-GEOD-71459 | biostudies-arrayexpress
ProteomicsQuantitative Proteomic Atlas of Ubiquitination in Hepatocellular Carcinoma
Ubiquitination plays a critical role in human hepatocellular carcinoma (HCC) genesis and metastasis, but how these processes affect systemic ubiquitinome still remains unclear. In this study, our dataset of around 12,000 diGly modified sites was identified providing a valuable insight into HCC. We f...
ORGANISM(S): Homo Sapiens 
2020-04-14 | PXD011895 |
ProteomicsQuantitative proteomic data of hepatocellular carcinoma
Ubiquitination plays a critical role in human cancer genesis and metastasis, but how the systemic ubiquitinome changes during these processes remains unclear. In this study, our dataset of approximately 12,000 identified ubiquitinated sites provided valuable insight into human hepatocellular carcino...
ORGANISM(S): Homo Sapiens 
2020-04-16 | PXD018593 |
ProteomicsIntegrative proteomics of macrophage in response to LPS stimulation
PTM proteomics had been increasingly used in studies related to inflammation and immunity, but the integrated analysis of multiple PTM was lacking. Here, we integrated WCP, acetylome, phosphoproteome and ubiquitinome datasets to identify LPS stimulation-dependent PTM events in macrophages with or wi...
ORGANISM(S): Homo Sapiens Mus Musculus 
2019-09-20 | PXD015527 |
ProteomicsCardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury
To elucidate the molecular mechanisms by which GPX4 regulates mitochondrial function, we overexpressed GPX4 in cardiomyocytes and subjected them to hypoxia-reoxygenation (H/R) modeling. Co-immunoprecipitation (Co-IP) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was employed...
ORGANISM(S): Mus Musculus 
2025-12-22 | PXD072382 |
Proteomicsdevelopment of prognostic biomarkers for HBV-related acute-on-chronic liver failure
development of prognostic biomarkers for HBV-related acute-on-chronic liver failure
ORGANISM(S): Homo Sapiens 
2020-03-07 | PXD017928 |
ProteomicsSS18 regulates pluripotent-somatic transition through phase separation
The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms m...
ORGANISM(S): Mus Musculus 
2021-05-23 | PXD026208 |
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