Sort   by:  
 Page size 
ProteomicsA Proteogenomic Analysis of Cervical Cancer Reveals Therapeutic and Biological Insights
We performed a comprehensive proteogenomic profiling of cervical cancer (CC) tumors obtained from 139 Chinese women. This study provides a valuable public resource including proteomic, phosphoproteome, acetylproteome for researchers and clinicians to delve deeper into molecular causes of CC, and to ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-09 | PXD055203 | Pride
Q-exactive hf-x Dia Phosphoproteome Tmt Q-exactive hf Timstof pro Acetylproteome Proteomic Cervical cancer 
ProteomicsOnline alkaline-pH reverse phase nanoelectrospray-tandem mass spectrometry complements conventional low-pH method for global proteomic analysis
The global proteome analysis was limited by the identification of peptides with low abundance or specific physiochemical properties. Here, a one-dimensional online alkaline-pH reverse phase nanoelectrospray-tandem mass spectrometry (AlkalinepH-MS/MS) method was developed and optimized for global pro...
ORGANISM(S): Homo Sapiens 
2023-01-15 | PXD039453 |
ProteomicsEndoglycosidases- treated N-glycosylation site identification
Glycoproteins, representing over 50% of human proteins and most biopharmaceuticals, are crucial for regulating various biological processes. The complexity of multiple glycosylation sites often leads to incomplete sequence coverage and ambiguous glycan modification profiles. Here, we developed an in...
ORGANISM(S): Homo Sapiens 
2024-12-30 | PXD059329 |
ProteomicsDecoding protein glycosylation by an integrative mass spectrometry-based de novo sequencing strategy
Glycoprotein is one of the most complex biomacromolecule，accounting for over 50% of total human proteins and the majority of biopharmaceuticals, exerting profound influences on various essential biological processes. With multiple N-glycosylation sites and O- glycosylation sites on the protein backb...
ORGANISM(S): Homo Sapiens Bos Taurus 
PXD055221 |
ProteomicsIntegrated Single-Cell Proteomics Analysis on an Active Matrix Digital Microfluidic Chip
We introduce and implement a comprehensive single-cell proteomics sample pre-treatment solution based on an active matrix digital microfluidics chip(AM-DMF-SCP). This platform accommodates high-throughput single-cell isolation and seamless, non-destructive sample pre-treatment, characterized by its ...
ORGANISM(S): Homo Sapiens 
PXD048434 |
ProteomicsProteomics of Cerebrospinal fluid from COVID-19 Patients with Neurological Manifestations
We reported a case series of 8 patients with prominent new-onset neurological manifestations, who were screened out from a patch of 304 COVID-19 confirmed patients. Proteomics were conducted in the simultaneously obtained CSF and serum samples of the enrolled patients, with three non-COVID-19 patien...
ORGANISM(S): Homo Sapiens 
2021-11-15 | PXD029740 |
ProteomicsProteome of Mpox virus A5L-expressing HEK293T cells
In this research, to discover the interactions of mpox-A5 with host proteins, HEK293T cells were utilized and transfected with pCAGGS-HA-A5L plasmid (or pCAGGS-HA plasmid), harvested at 24h, Heterologous expression of MPXV A5L in HEK293T cells was performed for Co-IP with anti-HA beads, and Immunobl...
ORGANISM(S): Homo Sapiens 
2024-11-13 | PXD057872 |
ProteomicsMETTL3 acetylation sites recognition
We performed stable isotope labeling of amino acids in cell culture (SILAC) and mass spectrometry (MS) analysis to identify potential acetylation sites on METTL3 in response to ectopic p300 expression.
ORGANISM(S): Homo Sapiens 
2021-08-28 | PXD028177 |
ProteomicsCirculating Exosomes proteome of Colorectal Cancer Based on Rapid DIA-MS
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
2019-10-20 | PXD015921 |
ProteomicsProteomics dataset of COVID-19 and control patients
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
PXD029023 |
Sort   by:  
 Page size