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MetabolomicsBlood pseudotargeted metabolome of moyamoya disease

We aimed to identify specific metabolomic changes and biomarkers for the differential clinical diagnosis of different subtypes of moyamoya disease (MMD). We conducted an pseudotargeted metabolomics analysis and pseudotargeted metabolomics analysis revealed decreased LPC expression in patients wit...

2024-10-31 | MTBLS10304 | MetaboLights
ProteomicsProteomic analysis of human circulating neutrophils upon multi states
Neutrophils exhibited remarkable plasticity and heterogenicity in both homeostasis and pathology conditions. Here, we conducted a “multi-states” proteomics methodology to explore how neutrophils respond upon infection and inflammation stress including bacterial analog LPS, virus analog Poly(I:C), pr...
ORGANISM(S): Homo Sapiens 
2024-12-23 | PXD059138 |
ProteomicsChronotoxici-plate Containing Rhythmic Liver Organoids for Drug Screening
The circadian clock coordinates the daily rhythmicity of biological processes, and its dysregulation is associated with various human diseases. Despite the direct targeting of rhythmic genes by many best-selling and WHO essential drugs, traditional approaches can’t satisfy the need of explore multi-...
ORGANISM(S): Mus Musculus 
PXD043268 |
ProteomicsProteins interacting with GBP5 and RSV-SH protein
HEK293T were transfected with RSV-SH-HA, GBP5-HA or VR1012(empty vector) respectively for 48 h and then harvested. Co-IP assay were performed with HA beads (Roche, catalog no. 11867423001), the elution was analyzed by mass spectrum. Mass spectrum analysis were performed by the national center for pr...
ORGANISM(S): Homo Sapiens 
PXD054621 |
ProteomicsClinical proteomics analysis using Data Independent Acquisition-Mass Spectrometry (DIA-MS) identified classifiers for molecular characterization of Lymphoma
In this study, we conducted a proteomics analysis on 109 fresh-frozen lymph node samples from clinical patients, covering a comprehensive suite of lymphoma subtypes including B-NHL, T-NHL, HL, Lymphadenitis, Tumor metastatic lymph node (TLN), and Non-neoplastic lymph node (TNM: N0).
ORGANISM(S): Homo Sapiens 
2020-01-15 | PXD017096 |
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