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MetabolomicsExtracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
The accumulation of acidic metabolic waste products within the tumor microenvironment profoundly inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it is unclear whether extracellular-acidosis impacts T cell metabolic fitness and differentiation status. Here, we surprisin...
2023-01-17 | MTBLS6661 | MetaboLights
UnknownJoint Association of Dietary Protein Intake and Eating Habits with the Risk of Gestational Diabetes Mellitus: A Case-Control Study.
Not available
S-EPMC10610363 | biostudies-literature
UnknownA Novel Three-Point Localization Method for Bladder Volume Estimation.
Not available
S-EPMC10975550 | biostudies-literature
ProteomicsComparative proteomic analysis revealed the differential responses to novel duck reovirus infection in the bursa of Fabricius of Cairna moschata
Duck reovirus (DRV) is well-studied aquatic bird virus belonging to the Orthoreovirus genus of the Reoviridae family. The bursa of Fabricius is an immunologically organ against virus invasion. However, the responses of the bursa of Fabricius of Cairna moschata to DRV infection are largely unknown. T...
ORGANISM(S): Cairina moschata 
2022-08-12 | PXD025093 | Pride
Cairna moschata  differential accumulated protein  reovirus  proteomic analysis  the bursa of fabricius 
TranscriptomicsExpression data from Th2 cell of ECM1 KO mice vs WT mice
CD4+ helper T cells are critical for immunological response. Th2 cells, a subset of CD4+ helper T cells, are responsible for asthma and other immune diseases. We found a Th2 secreted protein, ExtraCellular Matrix protein 1 (ECM1), which is highly induced by classic IL-4 signaling pathway during help...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-19707 | biostudies-arrayexpress
UnknownSingle-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy.
Not available
S-EPMC9418739 | biostudies-literature
ProteomicsRats, Brain, LC-MSMS - iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke
In our study, we apply isobaric tag for relative and absolute quantitation (iTRAQ) followed by multidimensional liquid chromatography and tandem MS analysis(LC-MS-MS). The iTRAQ labeling were performed according to the manufacturer's protocol (Applied Biosystems).8 groups of samples were labeled and...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD006437 | Pride
Lc-msms Brain Rats 
TranscriptomicsGenome-wide analysis of CD8 cells laser captured from skin biopsies during the mucocutaneous HSV-2 reactivation
Analysis of CD8 cells at the gene expression level during the genital HSV-2 reactivation. We would like to get a comprehensive overview on gene expression of CD8 T-cells during the post healing phases of HSV-2 reactivation. The hypothesis is that CD8 T-cells play a immune surveillance function durin...
ORGANISM(S): Homo sapiens 
2012-07-25 | E-GEOD-39625 | biostudies-arrayexpress
UnknownDownregulation of KIF1B mRNA in hepatocellular carcinoma tissues correlates with poor prognosis.
Not available
S-EPMC4507112 | biostudies-literature
ProteomicsSalivary Protein Biomarker Detection of Saliva Secretion Disorder in a Primary Sjögren Syndrome Murine Model
Decreased salivary flow is one of the most common symptoms in primary Sjögren syndrome (pSS). The present study was designed to identify a salivary protein biomarker related to saliva secretion disorder in NOD/ShiLtJ mice, a pSS primary murine model. The stimulated saliva was collected from NOD/ShiL...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-21 | PXD008199 | Pride
Biomarker  saliva secretion disorder  sjögren syndrome  saliva  differential proteomic analysis 
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