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MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
TranscriptomicsmiRNA expression profile analysis of Clonorchis sinensis by Solexa deep sequencing
Clonorchis sinensis is a zoonotic parasite causing clonorchiasis associated with human diseases such as biliary calculi, cholecystitis, liver cirrhosis, and is classified as carcinogenic to humans for cholangiocarcinoma. MicroRNAs (miRNAs) are non-coding, regulating small RNA molecules essential for...
ORGANISM(S): Clonorchis sinensis 
2010-09-03 | E-GEOD-22244 | biostudies-arrayexpress
MetabolomicsSulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
MetabolomicsLung Lipidomic Alterations in Beagle Dogs Infected with Toxocara canis

Toxocariasis, mainly caused by Toxocara canis, and to a lesser extent, Toxocara cati, is a neglected parasitic zoonosis. The mechanisms that underlie the changes in lipid metabolism of T. canis infection in Beagle dogs' lungs remain unclear. Lipidomics is a rapidly emer...

2023-08-21 | MTBLS5583 | MetaboLights
ProteomicsComparative proteomic analysis of Toxoplama gondii PRU oocyst during sporulation
The comparative proteomics research of Toxoplasma gondii oocyst during sporulation
ORGANISM(S): Toxoplasma gondii type III 
2016-07-21 | PXD003765 | Pride
Toxoplasma gondii Oocyst Itraq Lc-ms/ms 
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
UnknownOral Pathobionts Aggravate Myocardial Infarction Through Mobilization of B2 Cells.
Not available
S-EPMC12594163 | biostudies-literature
UnknownMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry.
Not available
S-EPMC4726199 | biostudies-literature
MetabolomicsThe Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
ProteomicsFirst Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
Lysine malonylation (Kmal) is a new posttranslational modification (PTM), which has been reported in several prokaryotic and eukaryotic species. Although Kmal can regulate many and diverse biological processes in various organisms, knowledge about this important PTM in the apicomplexan parasite Toxo...
ORGANISM(S): Toxoplasma gondii 
2020-05-27 | PXD015809 | Pride
Post-translational  modifications Toxoplasma gondii Malonylome Lysine malonylation 
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