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MetabolomicsMetabolic biomarkers of gastric cancer

Plasma samples were analyzed using UPLC-MS/MS untargeted metabolomics. The dataset comprised 144 participants. Partial least squares discriminant analysis (PLS-DA) three-dimensional scores plot distinguishing GC patients from non-GC controls. Metabolic profiling and differential comparison identi...

2026-09-29 | MTBLS12684 | MetaboLights
TranscriptomicsSystematic Transcriptome Analysis of Zebrafish Model of Diamond-Blackfan Anemia from RPS24 Deficiency (mRNA-Seq)
In this study, we found RPS24 is required for both the primitive hematopoiesis and definitive hematopoiesis process partly mediated by P53 pathway. With the RNA-seq and miRNA-seq technique, several deregulated genes and miRNAs were found to be related with hematopoiesis, vascular development and apo...
ORGANISM(S): Danio rerio 
2015-05-18 | E-GEOD-54152 | biostudies-arrayexpress
TranscriptomicsSystematic Transcriptome Analysis of Zebrafish Model of Diamond-Blackfan Anemia from RPS24 Deficiency (miRNA-Seq)
In this study, we found RPS24 is required for both the primitive hematopoiesis and definitive hematopoiesis process partly mediated by P53 pathway. With the RNA-seq and miRNA-seq technique, several deregulated genes and miRNAs were found to be related with hematopoiesis, vascular development and apo...
ORGANISM(S): Danio rerio 
2015-05-18 | E-GEOD-54259 | biostudies-arrayexpress
TranscriptomicsAssessment of hematopoietic failure due to RPL11 deficiency in a zebrafish model of DiamondM-bM-^@M-^SBlackfan anemia by deep sequencing
To comprehensively reflect the impact of RPL11 deficiency on the transcriptome of zebrafish embryos, we collected 40M-bM-^@M-^S50 RPL11-deficient and MO control zebrafish embryos at 48 hpf from separate experiments and constructed two mRNA-seq sequencing libraries in parallel. High-throughput sequen...
ORGANISM(S): Danio rerio 
2014-01-21 | E-GEOD-51326 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the Zebrafish model of Diamond-Blackfan Anemia from RPS19 deficiency via p53-dependent and -independent pathways
To determine the effect on the whole transcriptome of RPS19 morpholino and to identify the function of p53 in RPS19-deficient embryos, we analyzed the genome-wide transcript profiles of control morpholino (control), RPS19 morpholino knockdown (RPS19 MO), and RPS19 and p53 morpholino knockdown simult...
ORGANISM(S): Danio rerio 
2013-10-09 | E-GEOD-45699 | biostudies-arrayexpress
ProteomicsGlobal quantification of glutathione S-transferases in human serum using LC-MS/MS coupled with affinity enrichment
The concentrations of glutathione S-transferases (GSTs) in serum are considered disease biomarkers. Members of the GST superfamily often exhibit functional overlap, and can compensate for each other. Global and quantitative evaluation of serum GSTs is therefore urgent, but we currently lack an effic...
ORGANISM(S): Homo Sapiens 
2022-01-19 | PXD031061 |
TranscriptomicsFoxf1 enchances pulmonary inflammation and mastocytosis
The Forkhead Box f1 (Foxf1) transcriptional factor (previously known as HFH-8 or Freac-1) is expressed in endothelial and smooth muscle cells in the embryonic and adult lung. To assess effects of Foxf1 during lung injury, we used CCl4 injury model. Foxf1+/- mice developed severe airway obstruction ...
ORGANISM(S): Mus musculus 
2008-09-04 | E-GEOD-11112 | biostudies-arrayexpress
ProteomicsUbiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
Ubiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
ORGANISM(S): Oryza Sativa 
2017-12-11 | PXD023306 |
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