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ProteomicsAn integrated metabolomics and lipidomics approach for the study of metabolic network and early diagnosis in cerebral infarction
Cerebral infarction (CI) remains a major cause of high mortality and long-term disability worldwide. The exploration of biomarkers and pathogenesis is crucial for early diagnosis of CI. Although the understanding of metabolic perturbations underlying CI has increased in recent years, the relationshi...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036199 | Pride
Metabolomics Cerebral infarction Lc-ms Lipidomics Biomarkers 
MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsIdentification and sequencing of CD36 interacting proteins in cardiomyocytes
Identification and sequencing of CD36 interacting proteins in cardiomyocytes
ORGANISM(S): Mus Musculus 
2024-10-11 | PXD056711 |
ProteomicsDisruption of MerTK Increases the Efficacy of Checkpoint Inhibitor by Enhancing Ferroptosis and Immune Response in Hepatocellular Carcinoma
To investigate the potentail anti-PD-L1 resistance mechanism in HCC, we examine the different proteins between hepa1-6 and res1-6 tumor cells. Proteins were digested with trypsin and following by high-resolution liquidchromatography-tandem MS(LC-MS/MS) analysis
ORGANISM(S): Mus Musculus 
2023-12-21 | PXD048069 |
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
ProteomicsThe targets study of HDCA in ameliorating NAFLD induced by high-calories diet by multi-omics technology
HDCA supplementation ameliorated diet-induced NAFLD in C57 wild type mice. In attempt to comprehensively understand the molecular mechanism occurring during the protective effect of HDCA, transcriptomic and proteomic profiles of mouse liver were first analyzed utilizing RNA-Sequencing and Tandem Mas...
ORGANISM(S): Mus Musculus 
2023-08-18 | PXD044613 |
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