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ProteomicsCharacterization of ZIC4 role in choroid plexus carcinoma
ZIC4 is a transcription factor related to pathways like NOTCH and Sonic Hedgehog (Shh) pathways which are involved in choroid plexus carcinoma (CPC). The current study describes the effect of ZIC4 gene re-expression on a CPC cell line proteome. We performed SILAC-based proteomics of ZIC4-transfected...
ORGANISM(S): Homo sapiens (Human) 
2024-07-26 | PXD043748 | Pride
Lc-msms Cche-45 Choroid plexus carcinoma Silac Zic4 
GenomicsThe transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra.
The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra.
PRJNA785876 | ENA
GenomicsThe transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra
The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra
PRJNA789925 | ENA
UnknownEpigenetic silencing of ZIC4 contributes to cancer progression in hepatocellular carcinoma.
Not available
S-EPMC7584641 | biostudies-literature
TranscriptomicsThe transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra
Purpose: The mechanisms driving epithelial cell fate decisions to create differentiated body structures (such as tentacles and basal disk) are not understood in Hydra. We explored the role of Wnt signaling targets Zic4 and Sp5 in this process. Methods: RNA sequencing of differentiated body parts (te...
ORGANISM(S): Hydra vulgaris 
2022-12-31 | GSE191177 | GEO
UnknownCommon Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
Not available
S-EPMC10052809 | biostudies-literature
TranscriptomicsThe transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra.
A Zic4-dependent switch in Hydra turns tentacle into foot cells.
ORGANISM(S): Hydra vulgaris 
2023-01-01 | GSE190110 | GEO
UnknownEpigenetic silencing of ZIC4 unveils a potential tumor suppressor role in pediatric choroid plexus carcinoma.
Not available
S-EPMC11393135 | biostudies-literature
UnknownZic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis.
Not available
S-EPMC2268115 | biostudies-literature
UnknownNeural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Not available
S-EPMC7701213 | biostudies-literature
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