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ProteomicsCharacterization of ZIC4 role in choroid plexus carcinoma
ZIC4 is a transcription factor related to pathways like NOTCH and Sonic Hedgehog (Shh) pathways which are involved in choroid plexus carcinoma (CPC). The current study describes the effect of ZIC4 gene re-expression on a CPC cell line proteome. We performed SILAC-based proteomics of ZIC4-transfected...
ORGANISM(S): Homo sapiens (Human) 
2024-07-26 | PXD043748 | Pride
Lc-msms Cche-45 Choroid plexus carcinoma Silac Zic4 
UnknownLC3A Silencing Hinders Aggresome Vimentin Cage Clearance in Primary Choroid Plexus Carcinoma.
Not available
S-EPMC5556083 | biostudies-literature
UnknownStructure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma.
Not available
S-EPMC6522981 | biostudies-literature
UnknownEpigenetic silencing of ZIC4 unveils a potential tumor suppressor role in pediatric choroid plexus carcinoma.
Not available
S-EPMC11393135 | biostudies-literature
UnknownAcute promyelocytic leukemia in children cancer hospital Egypt.
Not available
S-EPMC11166612 | biostudies-literature
UnknownPreclinical validation of a novel therapeutic strategy for choroid plexus carcinoma.
Not available
S-EPMC10174050 | biostudies-literature
ProteomicsLC3A and Aggresomes: A trigger for UPR-activation, mitochondrial dysfunction, and cellular senescence
The protein quality control (PQC) network is crucial for maintaining cellular proteostasis by monitoring protein production, folding, and degradation. Unfolded protein response (UPR) and autophagy are key components of this network along with the compartmentalization of misfolded proteins into inclu...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD043703 | Pride
Autophagy  carcinoma  choroid plexus  endoplasmic reticulum  inclusion bodies  map1lc3a  mitochondria  proteomics  proteostasis  senescence 
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