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UnknownLoss of ZNF451 mediates fibroblast activation and promotes lung fibrosis.
Not available
S-EPMC11008011 | biostudies-literature
UnknownStructural basis for catalytic activation by the human ZNF451 SUMO E3 ligase.
Not available
S-EPMC4709122 | biostudies-literature
UnknownLncRNA BC032020 suppresses the survival of human pancreatic ductal adenocarcinoma cells by targeting ZNF451.
Not available
S-EPMC5843399 | biostudies-literature
UnknownSingle-Cell Spatial-Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8+ T Cell Dysfunction.
Not available
S-EPMC11555180 | biostudies-literature
UnknownAlternative splicing and co-option of transposable elements: the case of TMPO/LAP2α and ZNF451 in mammals.
Not available
S-EPMC4495291 | biostudies-literature
UnknownZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Not available
S-EPMC5623066 | biostudies-literature
ProteomicsA short SUMOylation tag modulates transcription factor activity
This research demonstrates that a short peptide, composed of residues 24-55 of ZNF451, is sufficient to induce SUMOylation of target proteins, both in vitro and in human cells. Increased SUMOylation of the transcription factor p53 via fusion with the ZNF451 peptide inhibits its transcriptional activ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD068083 | Pride
Sumo e3 ligase Small ubiquitin-like modifier (sumo) Transcription factor Sumoylation tag Znf451 Sumoylation P53 
UnknownIntegrated Genomic Approaches to Elucidate the Genetic Basis of Brugada Syndrome in Taiwanese Patients.
Not available
S-EPMC12547146 | biostudies-literature
UnknownSUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome.
Not available
S-EPMC10396300 | biostudies-literature
ProteomicsSUMO Activated Target Traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
Ubiquitin and ubiquitin-like conjugation cascades consist of dedicated E1, E2 and E3 enzymes with E3s providing substrate specificity. Mass spectrometry-based approaches have enabled the identification of more than 60,000 acceptor sites for ubiquitin and 40,000 acceptor sites for SUMO2/3. However, E...
ORGANISM(S): Homo sapiens (Human) 
2023-08-03 | PXD038326 | Pride
E3 enzymes Sumo1 Sumo2 
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