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ProteomicsIdentification ubiquitination of EGFR by LC-MS/MS
Previously, analysis of EGF-induced EGFR ubiquitination by mass spectrometry revealed that ubiquitinated lysine residues were located in the TKD of EGFR. However, the specific lysine residues for the CBL-mediated polyubiquitination have not been identified. To investigate the differences in EGFR ubi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024279 | Pride
Cbl Ubiquitination Znrf1 Egfr Lc-ms/ms 
TranscriptomicsComprehensive the effect of ZNRF1 on TLR3 activation in bone marrow-derived macrophages upon poly(I:C) stimulation
To evaluate comprehensively the effect of ZNRF1 on TLR3 activation, we stimulated WT or Znrf1 knockout BMDM with poly(I:C) for 4 hours. We then performed gene expression profiling analysis using data obtained from RNA-seq of duplicate samples.
ORGANISM(S): Mus musculus 
2023-04-10 | GSE226295 | GEO
GenomicsComprehensive the effect of ZNRF1 on TLR3 activation in bone marrow-derived macrophages upon poly(I:C) stimulation
Comprehensive the effect of ZNRF1 on TLR3 activation in bone marrow-derived macrophages upon poly(I:C) stimulation
PRJNA939551 | ENA
UnknownOxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration.
Not available
S-EPMC4657170 | biostudies-literature
UnknownThe ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.
Not available
S-EPMC5472178 | biostudies-literature
UnknownZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation.
Not available
S-EPMC8118649 | biostudies-literature
UnknownMyeloid ZNRF1 suppresses autoimmune demyelination and neuroinflammation by regulating MHC-II-mediated T cell activation.
Not available
S-EPMC12542093 | biostudies-literature
UnknownThe Src-ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage.
Not available
S-EPMC10174191 | biostudies-literature
UnknownStructural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.
Not available
S-EPMC5941314 | biostudies-literature
UnknownThe Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy.
Not available
S-EPMC10869362 | biostudies-literature
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