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ProteomicsImmunoproximity biotinylation reveals the axon initial segment proteome
The axon initial segment (AIS) is a specialized neuronal compartment required for action potential generation and neuronal polarity. However, understanding the mechanisms regulating AIS structure and function has been hindered by an incomplete knowledge of its molecular composition. Here, using immu...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-02 | PXD045921 | Pride
Axon initial segment Neuron Proteomics Proximity labeling Scrib Ankyring 
TranscriptomicsA global analysis of tandem 3'UTRs in eosinophilic chronic rhinosinusitis with nasal polyps
Background: Alternative polyadenylation (APA) is emerging as a widespread mechanism of gene regulation. The usage of APA sites allows a single gene to encode multiple mRNA transcripts with different 3'-untranslated region (3'UTR) lengths. Many disease processes reflect the importance of the regulati...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-39957 | biostudies-arrayexpress
UnknownTandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids.
Not available
S-EPMC4610815 | biostudies-literature
ProteomicsSpatially resolved mapping of proteome turnover dynamics with subcellular precision
We report the development of prox-SILAC method that combines proximity-dependent protein labeling (APEX/HRP) with metabolic incorporation of stable isotopes (pulse-SILAC) to map newly synthesized proteins with subcellular spatial resolution. We apply prox-SILAC to investigate proteome dynamics in th...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037569 | Pride
Pusle-silac Proximity-dependent labeling Protein turnover 
ProteomicsGenetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome
Mapping the subcellular organization of proteins is crucial for understanding their biological functions. Herein, we report a reactive oxygen species induced protein labeling and identification (RinID) method for profiling subcellular proteome in the context of living cells. Our method capitalizes o...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD037678 | Pride
Minisog sopp3 proximity labeling photosensitive protein singlet oxygen 
ProteomicsGenetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome
Mapping the subcellular organization of proteins is crucial for understanding their biological functions. Herein, we report a reactive oxygen species induced protein labeling and identification (RinID) method for profiling subcellular proteome in the context of living cells. Our method capitalizes o...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD034532 | Pride
Minisog  proximity labeling  photocatalytic  lc-msms 
TranscriptomicsDynamic profile of gene expression in rice panicle under high temperature
To comprehend the profile of rice gene expression at reproductive stage under high temperature, Agilent 4M-CM-^W44k rice oligo microarray experiments were carried out using rice panicle of developmental stage 7-9 at 0min, 20min, 1hr, 2hr, 4hr, and 8hr after the treatment of 40 degree centigrade, and...
ORGANISM(S): Oryza sativa 
2012-11-28 | E-GEOD-38665 | biostudies-arrayexpress
UnknownPartial hepatectomy versus interventional treatment in patients with hepatitis B virus-related hepatocellular carcinoma and clinically significant portal hypertension: a randomized comparative clinical trial.
Not available
S-EPMC11570767 | biostudies-literature
UnknownMagnetic resonance imaging and dynamic X-ray's correlations with dynamic electrophysiological findings in cervical spondylotic myelopathy: a retrospective cohort study.
Not available
S-EPMC7541238 | biostudies-literature
UnknownDeep neural network classification based on somatic mutations potentially predicts clinical benefit of immune checkpoint blockade in lung adenocarcinoma.
Not available
S-EPMC7051190 | biostudies-literature
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