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MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
MetabolomicsExploring the Interspecific Interactions and the Metabolome of the Soil Isolate Hylemonella gracilis
Analysis of aquatic microbial communities revealed that parts of its diversity consist of bacteria with cell sizes of ~0.1 μm. Such bacteria can show genomic reductions and metabolic dependencies with other bacteria. So far, no study investigated if such bacteria exist in terrestrial environments e....
2022-12-14 | MTBLS5841 | MetaboLights
UnknownAre Patient Expectations and Illness Perception Associated with Patient-reported Outcomes from Surgical Decompression in de Quervain's Tenosynovitis?
Not available
S-EPMC8052037 | biostudies-literature
UnknownNivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial.
Not available
S-EPMC6075855 | biostudies-literature
TranscriptomicsHigh content imaging in the screening of biomaterial-induced MSC behavior
Upon contact with a biomaterial, cells and surrounding tissues respond in a manner dictated by the physicochemical and mechanical properties of the material. Traditionally, cellular responses are monitored using invasive analytical methods that report the expression of genes or proteins. These analy...
ORGANISM(S): Homo sapiens 
2018-11-10 | E-MTAB-7352 | biostudies-arrayexpress
ProteomicsThe Histone Demethylase KDM5C Functions as a Tumor Suppressor in AML by Repression of B ivalently M arked Immature Genes
To uncover novel epigenetic regulators in AML, we performed an in vivo short hairpin RNA (shRNA) screen in the context of Cebpa mutant AML. This led to the identification of the Histone 3 Lysine 4 (H3K4) demethylase, KDM5C, as a novel tumor suppressor in AML. KDM5C potentially functions as a transcr...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD016568 | Pride
Human Leukemia Kdm5c 
GenomicsSeminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines (ChIP-seq data).
Background: Germ Cell Cancers (GCC), originating from Primordial Germ Cells /gonocytes, are the most common cancer in young men, subdivided in seminoma (SE) and non-seminoma (NS, stem cell component: embryonal carcinoma (EC)). Somatic mutations are rarely found in GCC. It has been proposed that disr...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56450 | biostudies-arrayexpress
UnknownExperimental and Theoretical Study of the Kinetics of Dimerization of Ammonia at Low Temperatures.
Not available
S-EPMC12278223 | biostudies-literature
UnknownInitial Decline (Dip) in Estimated Glomerular Filtration Rate After Initiation of Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction: Insights From DAPA-HF.
Not available
S-EPMC9354593 | biostudies-literature
UnknownSimultaneous Assessment of Urinary and Fecal Volatile Organic Compound Analysis in De Novo Pediatric IBD.
Not available
S-EPMC6832645 | biostudies-literature
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