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ProteomicsProteomic study identified several proteins involved in cellular processes in recurrent otitis media
Recurrent otitis (ROM) is a pathological conditions in which a children have at least three episodes of acute otitis media over a course of 6 months. In this study we focused in proteins dysregulated between ROM and adenotonsillar hypertrophy (ATH). Tissue sample of seven ROM and seven ATH were obta...
ORGANISM(S): Homo sapiens (Human) 
2020-12-10 | PXD022477 | Pride
2-de Recurrent otitis adenotonsillar hypertrophy Lc-ms/ms 
TranscriptomicsGlucose deprivation promotes lung adenocarcinoma de-differentiation due to unbalanced EZH2 activity
Lung cancer is the most frequent cancer-related cause of death, and adenocarcinoma (LUAD) is the most frequent type. Despite the recent success of immunotherapies, survival of lung cancer patients has not significantly improved in the last decades. New therapies are necessary. We have previously ide...
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-11253 | biostudies-arrayexpress
GenomicsGlucose deprivation promotes de-differentiation in lung adenocarcinoma
Increased utilization of glucose is a hallmark of cancer. Several studies are investigating the efficacy of glucose restriction on solid cancers, by glucose transporter blocking or glycolysis inhibition. However, the adaptations of cancer cells to glucose restriction are not known. Here, we report t...
ORGANISM(S): Homo sapiens 
2023-04-12 | E-MTAB-11678 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis thaliana seedlings after exposure to low R/FR light for a short and a long period of time
Aim of the experiment is the identification of regulatory genes rapidly induced by low R/FR and still up-regulated after prolonged exposure to FR-rich light. To this end, gene expression changes were analysed in Arabidopsis thaliana seedlings after exposure to low R/FR light for a short and a long p...
ORGANISM(S): Arabidopsis thaliana 
2006-03-01 | E-MEXP-443 | biostudies-arrayexpress
TranscriptomicsComparative Genomics Reveals New Molecular targets for Accelerated Improvement of Erythromycin-producing Strains
Information about molecular mechanisms underlying improvement of antibiotic-producing microorganisms with traditional mutation and screening approach is largely missing. This information is essential to develop rational approaches to strain improvement. In this study by using comparative genomic ana...
ORGANISM(S): Saccharopolyspora erythraea 
2012-05-23 | E-GEOD-30600 | biostudies-arrayexpress
GenomicsSalt priming A. thaliana ChIP-Seq
A role of chromatin in plant memory of environmental stress has been proposed. In this study ChIP-Seq was employed to investigate whether a transient mild salt treatment of Arabidopsis thaliana plant at seedling stage (M-^Qpriming treatmentM-^R: 50 mM NaCl for 24 hours) altered genome-wide profiles ...
ORGANISM(S): Arabidopsis thaliana 
2013-06-01 | E-MTAB-1663 | biostudies-arrayexpress
Unknown10 Years of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A Systematic Review and Meta-Analysis.
Not available
S-EPMC9954579 | biostudies-literature
TranscriptomicsThe nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 2
The RNA-binding protein Argonaute 2 (AGO2) is a key effector of RNA-silencing pathways It exerts a pivotal role in microRNA maturation and activity, and can modulate chromatin remodeling, transcriptional gene regulation and RNA splicing. The Estrogen Receptor beta (ERβ) is endowed with oncosuppressi...
ORGANISM(S): Homo sapiens 
2016-12-31 | E-MTAB-4639 | biostudies-arrayexpress
UnknownA dynamic interplay between chitin synthase and the proteins Expansion/Rebuf reveals that chitin polymerisation and translocation are uncoupled in Drosophila.
Not available
S-EPMC9894549 | biostudies-literature
UnknownPresepsin levels and COVID-19 severity: a systematic review and meta-analysis.
Not available
S-EPMC9666937 | biostudies-literature
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