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TranscriptomicsAnalysis of Gene expression of human Th17 and Th1 clones
Human T cell clones were derived according to standard protocols using different mix of cytokines, once assessed for their functional profile were studied for gene expression. The purpose of this study is to analyze human Th1 and Th17 clones with and without stimulation with PMA and Ionomycin to mea...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-30664 | biostudies-arrayexpress
TranscriptomicsWRKY6 Transcription Factor Restricts Arsenate Uptake and Transposon Activation in Arabidopsis
Stress constantly challenges plant adaptation to the environment. Of all stress types, arsenic was a major threat during the early evolution of plants. The most prevalent chemical form of arsenic is arsenate, whose similarity to phosphate renders it easily incorporated into cells via the phosphate...
ORGANISM(S): Arabidopsis thaliana 
2014-04-25 | E-GEOD-49037 | biostudies-arrayexpress
TranscriptomicsNF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation
In this study, analysis of miRNA expression changes in osteoclast differentiation from human primary monocytes revealed the rapid upregulation of two miRNA clusters, miR-212/132 and miR-99b/let-7e/125a. We demonstrate that they negatively target monocyte-specific and immunomodulatory genes like TNFA...
ORGANISM(S): Homo sapiens 
2014-12-03 | E-GEOD-63773 | biostudies-arrayexpress
TranscriptomicsIGR_Michels_PARP
Non-small cell lung cancer (NSCLC) is often treated with cisplatin (CDDP). Here, we report that two distinct poly(ADP-ribose) polymerase (PARP) inhibitors exhibited a hyperadditive combination effect with CDDP to kill NSCLC cells. A majority of CDDP-resistant cell lines and clones exhibited constitu...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-MTAB-1353 | biostudies-arrayexpress
Transcriptomicslung carcinoid
Global gene expression of 13 frozen samples, 6 from typical and 7 from atypical surgically resected primary lung carcinoids All the patients not chemo-radio naïve and with a second tumor were excluded from the study. A written informed consent for research use of biological samples was obtained fr...
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-35679 | biostudies-arrayexpress
TranscriptomicsHuman RORM-NM-3t+ CD34+ cells are lineage-specified progenitors of group 3 RORM-NM-3t+ innate lymphoid cells
Group 3 innate lymphoid cells (ILC3) are defined by the expression of RORM-NM-3t, which is selectively required for their development. The lineage-specified progenitor cells of human ILC3 and their developmental site after birth remain undefined. Here we identified a novel population of human CD34+ ...
ORGANISM(S): Homo sapiens 
2014-11-25 | E-GEOD-63197 | biostudies-arrayexpress
UnknownEffect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.
Not available
S-EPMC9073661 | biostudies-literature
UnknownMinimal manifestation status and prednisone withdrawal in the MGTX trial.
Not available
S-EPMC7455358 | biostudies-literature
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownReduced lung-cancer mortality with low-dose computed tomographic screening.
Not available
S-EPMC4356534 | biostudies-literature
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