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Liver and adipose tissue undergo dynamic inflammatory changes during the progression of obesity. This study was designed to evaluate the changes in gene expression profile and function of subpecific macophage subsets.
ORGANISM(S): Mus musculus 
2020-12-11 | GSE163003 | GEO
Macophage migration inhibitor (MIF) is important for MM resistance to proteasome inhibitors. To determine what signalling pathways are affected by MIF in MM cells, we established MIF-KO MM.1S and ARP-1 MM cell lines. Total RNAs of 2 x 106 CTR-KO and MIF-KO MM cells were extracted by RNeasy Mini Kit ...
ORGANISM(S): Homo sapiens 
2020-05-07 | GSE141170 | GEO
We generated Ikkα-KA/KA knock-in mice (KA/KA), in which an ATP binding site of Ikkα Lys 44 was replaced by alanine. The knock-in mice develop severe skin lesions and begin to die after 6 to 10 months. We also found lung SCCs in some of the mice. To study lung SCC development, we stabilize the skin c...
ORGANISM(S): Mus musculus 
2012-05-01 | GSE37655 | GEO
We generated Ikkα-KA/KA knock-in mice (KA/KA), in which an ATP binding site of Ikkα Lys 44 was replaced by alanine. The knock-in mice develop severe skin lesions and begin to die after 6 to 10 months. We also found lung SCCs in some of the mice. To study lung SCC development, we stabilize the skin c...
ORGANISM(S): Mus musculus 
The immunomodulatory effect of mung bean is mainly attributed to antioxidant properties of flavonoids; however, the precise machinery for biological effect on animal cells remains uncertain. The objective of this study was to understand the physiological change produced by mung bean consumption.
ORGANISM(S): Mus musculus (Mouse) 
2017-04-06 | PXD005330 | Pride
Expression data from control-knockout (CTR-KO) and MIF-KO human multiple myeloma (MM) cells
Macrophage heterogenity in liver and adipose during obesity
Gene expression alteration by macrophage depletion in IKKα mutant mice
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