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ProteomicsIdentification of a USP9X Substrate NFX1-123 by SILAC-based Quantitative Proteomics
The deubiquitinase USP9X related with multiple diseases including neurodegeneration, epilepsy and various type of tumor, by targeting different substrates. In our study, to deep study USP9X functional candidate substrates, we performed SILAC-based quantitative proteomic to compare knockdown USP9X w...
ORGANISM(S): Homo sapiens (Human) 
2019-05-13 | PXD012871 | Pride
Usp9x nfx1-123 silac 
ProteomicsProliferative proteome induced by HPV 16E6 and NFX1-123 partnership in longitudinal keratinocyte cultures
Human papillomaviruses (HPV) cause cervical, anogenital, and oropharyngeal cancers. Despite the availability of preventive HPV vaccines, their poor uptake leaves individuals at risk for these cancers, many of which remain common globally, and others that are increasing domestically. The HPV 16 E6 (1...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Papillomavirus (ncbitaxon:10566) 
2025-04-24 | MSV000097715 | MassIVE
TranscriptomicsExpression data from neonatal human foreskin keratinocytes (NHKs) with NFX1-123 endogenous expression, overexpression, or knocked down expression, with or without HPV16E6 co-expression
GSM1056261-GSM1056272: NFX1-123 has been shown to associate with a number of RNA processing proteins, such as cytoplasmic poly(A) binding proteins (PABPC), to affect mRNA stability and translational efficiency of target genes. The high-risk human papillomavirus type 16E6 (HPV 16E6) induces telomeras...
ORGANISM(S): Homo sapiens 
2013-10-15 | GSE43082 | GEO
UnknownCervical Cancer Development: Implications of HPV16 E6E7-NFX1-123 Regulated Genes.
Not available
S-EPMC8699269 | biostudies-literature
TranscriptomicsExpression data from neonatal human foreskin keratinocytes (NHKs) with NFX1-123 endogenous expression, overexpression, or knocked down expression, with or without HPV16E6 co-expression
GSM1056261-GSM1056272: NFX1-123 has been shown to associate with a number of RNA processing proteins, such as cytoplasmic poly(A) binding proteins (PABPC), to affect mRNA stability and translational efficiency of target genes. The high-risk human papillomavirus type 16E6 (HPV 16E6) induces telomera...
ORGANISM(S): Homo sapiens 
2013-10-15 | E-GEOD-43082 | biostudies-arrayexpress
UnknownGenes Regulated by HPV 16 E6 and High Expression of NFX1-123 in Cervical Cancers.
Not available
S-EPMC7326398 | biostudies-literature
UnknownHPV type 16 E6 and NFX1-123 augment JNK signaling to mediate keratinocyte differentiation and L1 expression.
Not available
S-EPMC6486444 | biostudies-literature
UnknownNFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.
Not available
S-EPMC1866132 | biostudies-literature
UnknownHuman papillomavirus type 16 E6 and NFX1-123 mislocalize immune signaling proteins and downregulate immune gene expression in keratinocytes.
Not available
S-EPMC5695606 | biostudies-literature
UnknownHuman papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest.
Not available
S-EPMC4383269 | biostudies-literature
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