spermatogenesis

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Organisms

Mus musculus (624)
Homo sapiens (112)
Drosophila melanogaster (46)
Caenorhabditis elegans (33)
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Oncorhynchus mykiss (4)
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pride (121)
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Tissue

Testis (76)
Sperm (21)
Cell culture (8)
Sertoli cell (4)
Spermatozoon (3)
Extracellular vesicle (3)
Brain (3)
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Male Reproductive System (2)
Spermatid (2)
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Leg (1)
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Disease

Infertility (8)
Not Available (6)
Male infertility (4)
Disease free (4)
Normal (3)
Azoospermia (2)
Oligoasthenoteratozoospermia (2)
Ejaculatory azoospermia (1)
Testicular seminoma (1)
Cryptorchidism (1)
Cryptozoospermia (1)
Postnatal day 18 was the earliest time point at which structural differences between testes from wild-type and pcd3J-/- mice were observed via histopathology. (1)
These mice have a relatively normal first wave of spermatogenesis but never become fertile. Older animals show increased apoptosis of germ cells, increasing in severity as germ cell stage advances. (1)
Azoospermia (1)
Oligospermia (1)
Zika fever (1)
Type 1 diabetes mellitus (1)
Obesity (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (121)
Shotgun proteomics (69)
Bottom-up proteomics (23)
Data-dependent acquisition (14)
Affinity purification coupled with mass spectrometry proteomics (12)
Gel-based experiment (8)
Mass spectrometry (5)
Data-independent acquisition (5)
Top-down proteomics (4)
Affinity proteomics (2)
Mass spectrometry imaging (1)
SWATH MS (1)
SRM/MRM (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

NextSeq 550 (13)
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Illumina NovaSeq 6000 (6)
Illumina HiSeq 4000 (6)
Instrument (6)
Orbitrap Fusion (3)
LTQ Orbitrap (3)
Scanning hardware (2)
Illumina NovaSeq X (2)
Illumina HiSeq 1500 (2)
Illumina HiSeq 2000 (2)
NextSeq 500 (2)
LTQ Orbitrap XL (2)
Liquid Chromatography MS - positive (2)
Liquid Chromatography MS - positive - reverse phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
Axon-GenePix 4100A (1)
454 GS FLX (1)
Intel Xeon E5-2660 (128G RAM) (1)
Illumina Genome Analyzer IIx (1)
Illumina Genome Analyzer II (1)
Ion Torrent Proton (1)
Illumina HiSeq 3000 (1)
Thermo QExactive HF (1)
NanoACQUITY UPLC (1)
LTQ (1)
TripleTOF 6600 (1)
Q Exactive HF (1)
Q Exactive (1)
Orbitrap Fusion Lumos (1)

Publication Date

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2026 (130)
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2021 (113)
2023 (95)
2014 (90)
2022 (81)
2020 (75)
2015 (75)
2010 (73)
2013 (70)
2018 (63)
2019 (57)
2012 (50)
2017 (47)
2016 (47)
2008 (40)
2011 (39)
2007 (24)
2009 (21)
2006 (13)
2005 (7)
2004 (5)
2003 (2)

UNIPROT ID/AC

Q9UHP6 (3)
Q9HAE3 (3)
Q9GZS0 (3)
Q99932 (3)
Q96M63 (3)
Q8WWB3 (3)
Q8NDM7 (3)
Q6URK8 (3)
Q5JST6 (3)
Q5BN46 (3)
P59910 (3)
A8MYP8 (3)
Q9Y615 (3)
Q9UK85 (3)
Q9UJT2 (3)
Q9UI46 (3)
Q9NWH7 (3)
Q9HBV2 (3)
Q9HAT0 (3)
Q9H1X1 (3)
Q9H0K4 (3)
Q9BZX4 (3)
Q9BYD9 (3)
Q9BY14 (3)
Q9BXF9 (3)
Q9BUN1 (3)
Q9BS86 (3)
Q96T59 (3)
Q96MR6 (3)
Q96M98 (3)

ENSEMBL ID

ENSG00000170477 (3)
ENSG00000214897 (2)
ENSG00000229353 (2)
ENSG00000247315 (2)
ENSG00000204131 (1)
ENSG00000147251 (1)

CHEBI ID

CHEBI:176360 (1)
CHEBI:176357 (1)
CHEBI:176349 (1)
CHEBI:176345 (1)
CHEBI:140611 (1)
CHEBI:31968 (1)
CHEBI:176352 (1)
CHEBI:31442 (1)
CHEBI:28299 (1)
CHEBI:75630 (1)
CHEBI:75632 (1)
CHEBI:75643 (1)
CHEBI:176355 (1)
CHEBI:80441 (1)
CHEBI:28064 (1)
CHEBI:176415 (1)
CHEBI:176414 (1)
CHEBI:172555 (1)
CHEBI:176413 (1)
CHEBI:176412 (1)
CHEBI:81563 (1)
CHEBI:34102 (1)
CHEBI:176411 (1)
CHEBI:176410 (1)
CHEBI:176409 (1)
CHEBI:168901 (1)
CHEBI:176408 (1)
CHEBI:176407 (1)
CHEBI:176406 (1)
CHEBI:67061 (1)

Metabolite Name

D-Lysine (2)
Arabinosylhypoxanthine (2)
Cinnamoylglycine (2)
Sphingosine (2)
Phenylacetylglutamine (2)
Serotonin (2)
Taurine (2)
Taurocholic acid (2)
Phenylacetylglycine (2)
Adenosine (2)
Uric acid (2)
Guanosine (2)
Creatine (2)
Glycerophosphocholine (2)
Hippuric acid (2)
Azulene, 1,4-dimethyl-7-(1-methylethyl)- (1)
PFSA-pentafluorosulfide (1)
Daptomycin (1)
7-[2-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-2-oxoethoxy]-3,4-dimethylchromen-2-one (1)
2-Acetamido-3-(1,3-Benzodioxol-5-Yl)-N-(Phenylmethyl)-2-Propenamide (1)
(1,3-dimethyl-2,6-dioxo(1,3-dihydropyrimidin-4-yl))-N-[2-(2-chlorophenoxy)ethy l]carboxamide (1)
Methyl 1-(4-fluorophenyl)-1,2,3,4-tetrahydrobeta-carboline-3-carboxylate (1)
1,4-Ethanonaphthalene-5,10-dicarboxylic acid, 1,4,4a,5,6,8a-hexahydro-5,10-dihydroxy-6,9-dioxo-, bis[[2-(beta-D-glucopyranosyloxy)-3-hydroxyphenyl]methyl] ester (1)
1-{[(3-Cyano-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-2-Yl)Sulfanyl]Acetyl}Proline (1)
Spegatrine (1)
1-(2,5-diphenyl(1,3-oxazol-4-yl))-5-chloro-1,3-dihydropyrimidine-2,4-dione (1)
N-(2-furylmethyl)(2-oxochromen-3-yl)carboxamide (1)
Chlorothalonil TP SYN548008 (1)
Agatholal (1)
Coumaroyl Hexoside (1)

First Public Date

2024 (158)
2025 (156)
2014 (146)
2026 (138)
2023 (119)
2021 (103)
2020 (86)
2022 (77)
2019 (65)
2018 (52)
2017 (51)
2015 (43)
2013 (38)
2016 (31)

Classification

helminths (4)

Study type

Transcription profiling by array (190)
RNA-seq of coding RNA (46)
ChIP-seq (25)
RNA-seq of non coding RNA (25)
RNA-seq of coding RNA from single cells (10)
Methylation profiling by high throughput sequencing (9)
ChIP-chip by tiling array (8)
Animal - Single-cell sequencing (5)
Unknown experiment type (3)
Animal - High-throughput sequencing (3)
Transcription profiling by tiling array (3)
Comparative genomic hybridization by array (3)
Methylation profiling by array (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
ChIP-chip by array (1)
Ribo-seq (1)
Other (1)
MicroRNA profiling by array (1)
DNA-seq (1)
CUT&RUN (1)

Release Date

2022 (425)
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2019 (229)
2017 (198)
2016 (198)
2015 (196)
2014 (184)
2018 (175)
2013 (145)
2011 (137)
2012 (136)
2010 (131)
2009 (83)
2008 (78)
2007 (53)
2026 (51)
2005 (30)
2006 (29)
2004 (20)
2002 (9)
2000 (9)
2001 (7)
2003 (5)
1998 (5)
1999 (4)

Lab affiliation

Lomonosov Moscow State University (4)
City University of Hong Kong (3)
EDyP (3)
Shandong University (3)
State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu,China. (2)
Université Paris Cité, INSERM, CNRS, Institut Cochin, F-75014 Paris, France (2)
The Concern Foundation Laboratories at The Lautenberg Center for Immunology and Cancer Research IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel (2)
Functional Proteomics Lab, Dpt. Life Sciences, University of Siena, Italy (2)
Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Prague, Czech Republic (2)
West China Second University Hospital, Sichuan University (2)
State Key Laboratory of Reproductive Medicine and Offspring Health， Nanjing Medical University, Nanjing, China. (2)
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences (2)
Cornell University (2)
Colorado Center for Reproductive Medicine, CO, USA (1)
Laboratory for RNA Cancer Biology Department of Oncology, LKI, KU Leuven (1)
School of BioSciences and Bio21 Institute, Faculty of Science, The University of Melbourne, VIC, 3010, Australia (1)
Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. (1)
College of Animal Science and Technology, Qingdao Agricultural University, China (1)
Department of Developmental Pathology and Department of Molecular Diagnostics Institute of Pathology Bonn Medical School Venusberg-Campus 1, Building 62 53127 Bonn (1)
State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu 210029, China. (1)
Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, München, Germany (1)
Insititute of Animal Sciences,Chinese Academy of Agricultural Sciences (1)
Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, Feodor-Lynen-Strasse 25, 81377 Munich, Germany (1)
Shanghai Ocean University (1)
Department of Biochemistry and Molecular Biology, State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100005, China (1)
Biogenouest Proteomics Core Facility IRSET – INSERM U1085 Rennes, France (1)
CEA-Marcoule, ProGenoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Ceze, France (lab head) (1)
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Animal Reproduction Institute, Guangxi University, Nanning, Guangxi, China (1)
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Animal Reproduction Institute, Guangxi University, Nanning 530004, Guangxi, PR China. (1)
Ghent University VIB Belgium (1)

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Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA

ZIKV infection is associated with testicular damage and abnormal spermatogenesis. However, the molecular mechanisms underlying these pathogenic processes remain unclear. Here, we demonstrate that ZIKV disrupts Leydig cells' ability to produce testosterone, leading to decreased sperm counts and mo...

2025-06-29 | MTBLS12549 | MetaboLights

Untargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men: A noninvasive detection of spermatogenesis

Male factor infertility is involved in almost half of all infertile couples. Lack of the ejaculated sperm owing to testicular malfunction has been reported in 6-10% of infertile men, a condition named nonobstructive azoospermia (NOA). In this study, we investigated untargeted metabolomic profiling o...

2018-04-19 | MTBLS420 | MetaboLights

Probiotics alleviated heat stress-induced spermatogenesis dysfunction by remodeling gut microbiota and producing arginine and pantothenic acid

BACKGROUND: Large-scale farms struggle to effectively address summer heat stress (HS) in dairy goats, which impairs spermatogenesis and reduces reproductive performance by compromising gut and reproductive organ health in male animals. Although Clostridium butyricum (CB) and Enterococcus faecium ...

2025-07-31 | MTBLS12573 | MetaboLights

RNA-Seq and RNA Polymerase II ChIP-Seq of mouse spermatogenesis

To characterize gene expression in spermatogenesis we sequenced eight mRNA samples from testes of juvenile mice aged between 6 and 38 days post partum. We then classified gene expression profiles and found over 1,000 meiotically-expressed protein-coding genes that have not been previously reported i...

ORGANISM(S): Mus musculus

2014-01-22 | E-GEOD-44346 | biostudies-arrayexpress

Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis.

Not available

S-EPMC3271663 | biostudies-literature

Tex10 in spermatogenesis

PRJNA785665 | ENA

Histone H3.3 regulates dynamic chromatin states during spermatogenesis

We used H3f3b-/- testes to analyze the impact of H3f3b derived H3.3 on spermatogenesis. Analysis of Histone H3 (Lys 4) tri-methylation in H3f3b WT/WT and H3f3b -/- testes tissue.

ORGANISM(S): Mus musculus

2014-09-09 | E-GEOD-60207 | biostudies-arrayexpress

Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction

The mammalian Y chromosome plays a critical role in spermatogenesis. However, the exact functions of each gene in the Y chromosome have not been completely elucidated, partly owing to difficulties in gene targeting analysis of the Y chromosome. Zfy was first proposed to be a sex determination factor...

ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088)

2016-11-24 | MSV000080355 | MassIVE

Kinases as targets for chemical modulators: Structural aspects and their role in spermatogenesis.

Not available

S-EPMC4581050 | biostudies-literature

High-Resolution Profiling of Novel Transcribed Regions During Rat Spermatogenesis

Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-depth analysis of the male germline protein-coding...

ORGANISM(S): Rattus norvegicus

2014-06-01 | E-GEOD-48321 | biostudies-arrayexpress

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