Sort   by:  
 Page size 
TranscriptomicsGene expression profiling of Lgr5 positive cells within intestinal adenomas
The generation of the Lgr5_EGFP_ires_CreERT2 knock-in mouse allows marking of Lgr5 positive cells of different tissues. Here we use these mice to sort Lgr5 positive cells and their daughter cells form intestinal adenomas and describe the expression profile of these two cell populations. Intestinal a...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-37926 | biostudies-arrayexpress
TranscriptomicsCOMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AGILENT ARRAYS)
The identification of Lgr5 as an intestinal stem cell marker has made it possible to isolate and study primary intestinal stem cells. Applying quantitative mass spectrometry as well as transcriptomic analysis, we profiled the protein and gene changes between FACS-sorted Lgr5+ve stem cells and their ...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-23672 | biostudies-arrayexpress
TranscriptomicsGene expression profiling along the intestinal crypt axis.
The identification of Lgr5 as an intestinal stem cell marker has made it possible to isolate and study primary intestinal stem cells. Transcriptional differences between intestinal stem cells can be explored by the use of the Lgr5-eGFP-ires-CreERT2 knock-in mouse. In this mouse model GFP expression ...
ORGANISM(S): Mus musculus 
2012-08-15 | E-GEOD-36497 | biostudies-arrayexpress
TranscriptomicsCOMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AFFYMETRIX ARRAYS)
The identification of Lgr5 as an intestinal stem cell marker has made it possible to isolate and study primary intestinal stem cells. Applying quantitative mass spectrometry as well as transcriptomic analysis, we profiled the protein and gene changes between FACS-sorted Lgr5+ve stem cells and their ...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-33948 | biostudies-arrayexpress
TranscriptomicsDll1 marks early secretory progenitors in gut crypts that can revert to stem cells upon tissue damage
The introduction of GFP into the Dll1 locus has made it possible to isolate and study primary intestinal Dll1 positive cells, which constitute the secretory cell precursors of the intestine. Applying DNA array technology, we profiled the RNA changes of FACS-sorted Dll1_high/CD24_low, Dll1_high/CD24_...
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-39915 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of TCF4 in human LS174AT cells using Nimblegen human genome-wide chips
genome-wide ChIP-on-chip against TCF4 in LS174T cells, performed on NimbleGen Systems, Inc. human genome-wide 38-chip, hg17 array set followed by verification using biological replicates on a dedicated design.
ORGANISM(S): Homo sapiens 
2008-02-13 | E-TABM-402 | biostudies-arrayexpress
TranscriptomicsProspective derivation of a 'Living Organoid Biobank' of colorectal cancer patients
In Rspondin-based three-dimensional cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. Here we report the establishment of tumor organoid cultures from 20 consecutive colorectal carcinoma (CRC) patients. For most, organoids were...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-65253 | biostudies-arrayexpress
TranscriptomicsLgr6 Marks Stem Cells in the Hair Follicle that Generate all Cell Lineages of the Skin
Mammalian epidermis consists of three self-renewing compartments: the hair follicle, sebaceous gland and interfollicular epidermis. We generated knock-in alleles of murine Lgr6, a close relative to the Lgr5 stem cell gene. Lgr6 was expressed in the earliest embryonic hair placodes. In adult hair fol...
ORGANISM(S): Mus musculus 
2010-03-25 | E-GEOD-20269 | biostudies-arrayexpress
Proteomics,MultiomicsMm_Stem_cell_dimethyl_ETD
Mouse Lgr5+ s stem cell, dimethyl labeling ETD
ORGANISM(S): Mus Musculus 
2012-12-31 | PAe003968 | PeptideAtlas
Proteomics,MultiomicsMm_Stem_cell_dimethyl_HCD
Mouse Lgr5+ s stem cell, dimethyl labeling HCD
ORGANISM(S): Mus Musculus 
2012-12-31 | PAe003967 | PeptideAtlas
Sort   by:  
 Page size