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ProteomicsSyntaxin-3 is a Weibel-Palade body localized SNARE protein that regulates Von Willebrand factor secretion from endothelial cells
Endothelial cells store von Willebrand factor (VWF) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab-effectors and SNARE proteins. We have previously identified STXBP1 as the link between the Rab27A-Slp4-a ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD006176 | Pride
Endothelial cells Proteomics Weibel-palade body Snare machinery Syntaxin-3 Von willebrand factor 
TranscriptomicsLmrR Lactococcus lactis MG1363
Comparison of L. lactis NZ9000 ?lmrR versus L. lactis NZ9000 wild type Keywords: Transcription profiling Comparison between strain lacking transcriptional regulator LmrR of major Lactococcal mdr transporter LmrCD, and wild type parental strain.
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
2007-10-04 | E-GEOD-9168 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to carbon limitation in aerobic chemostat cultures
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8088 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to fermentative conditions
The capacity of respiring cultures of Saccharomyces cerevisiae to instantaneously switch to fast alcoholic fermentation upon a transfer to anaerobic sugar-excess conditions is a key characteristic of Saccharomyces cerevisiae in many of its industrial applications. This transition was studied by expo...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8187 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to nitrogen limitation in chemostat culture
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8089 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast to investigate the involvement of Snf7 and Rim101 in regulation of TIR1 and anaerobically up-regulated genes
Despite the scientific and applied interest in anaerobic metabolism of Saccharomyces cerevisiae, not all genes whose transcription is up-regulated under anaerobic conditions have yet been linked to known transcription factors. Experiments with a reporter construct in which the promoter of the anaero...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-02 | E-GEOD-18128 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to zinc limitation in chemostat cultures
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8035 | biostudies-arrayexpress
UnknownA highly efficient and sustainable catalyst system for terminal epoxy-carboxylic acid ring opening reactions.
Not available
S-EPMC10948088 | biostudies-literature
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