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TranscriptomicsPancreatic endocrine tumours: expression profiling evidences a rold for AKT-mTOR pathway
We investigated the global gene expression in a large panel of pancreatic endocrine tumours (PETs) aimed at identifying new potential targets for therapy and biomarkers to predict patient outcome. Total RNA was extracted from frozen tissue and hybridized on a custom 18.5K human oligo microarrays obt...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-73338 | biostudies-arrayexpress
TranscriptomicsRenal Cell Carcinoma Differential Expression
We investigated the changes in gene expression accompanying the development and progression of kidney cancer using 31,500 element complementary DNA arrays. We measured expression profiles for paired neoplastic and non-cancerous renal epithelium samples from 37 individuals. Using an experimental desi...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-3 | biostudies-arrayexpress
UnknownMucin 1-specific active cancer immunotherapy with tecemotide (L-BLP25) in patients with multiple myeloma: an exploratory study.
Not available
S-EPMC4514088 | biostudies-literature
ProteomicsA synthetically methylotrophic Escherichia coli as a chassis for bioproduction
Proteome characterization of three E. coli strains: a methanol-dependent strain (MEvo1-0) and two synthetically methylotrophic strains (MEcoli_ref_1, MEcoli_ref_2)
ORGANISM(S): Escherichia coli 
2024-02-08 | PXD046243 | Pride
Synthetic biology Metabolic engineering Synthetic methylotrophy Biotechnology E. coli 
UnknownChromosomal clustering of a human transcriptome reveals regulatory background.
Not available
S-EPMC1261156 | biostudies-literature
TranscriptomicsExpression data from 5 day old Arabidopsis thaliana seedlings
Upon induction of DNA damage Arabidopsis thaliana plants initiate a transcriptional response program governed by signalling cascades which are activated by the ATM and ATR kinases To analyse if the ATM dependent gene GMI1 (At5G24280) is involved in the regulation of the transcriptionl response, we c...
ORGANISM(S): Arabidopsis thaliana 
2011-04-21 | E-GEOD-23892 | biostudies-arrayexpress
TranscriptomicsIdentification of KDM3A regulated genes in the ER positive breast cancer cell line MCF-7
Using a siRNA screen we identified the histone demethylase enzyme KDM3A as a potential positive regulator of ER signalling in breast cancer. To interrogate the full extent of KDM3A regulation on ER signalling we assessed basal and estrogen (E2)- stimulated global gene expression changes in KDM3A-dep...
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-68918 | biostudies-arrayexpress
TranscriptomicsTranscription profling of human neuroblastoma samples to construct, validate and evalute a gene expression based classification of outcome of treatment
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2009-02-17 | E-TABM-38 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chromic myeloid leukemia (CML) patients treated second-line with imatinib after failure of an interferon-alpha based therapy to identify genes with predictive value for primary cytogenetic outcome to imatinib
Identification of genes in CML patients with predictive value for their primary cytogenetic outcome to imatinib. All samples analyzed were taken just before the start of imatinib treatment. Leukemic patients were treated second-line with imatinib after failure of an interferon-alpha based therapy (f...
ORGANISM(S): Homo sapiens 
2006-05-31 | E-MEXP-433 | biostudies-arrayexpress
TranscriptomicsCASPAR survival analysis
This set of profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2008-12-31 | E-MTAB-16 | biostudies-arrayexpress
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