Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-5761

ABSTRACT: Gene expression profiling of peripheral blood mononuclear cells (PBMCs) 8 hours after exposure to 1 Gy of carbon or iron ions

PROVIDER: E-MTAB-5761 | ExpressionAtlas | 2025-01-23

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-5761-analysis-methods.tsv	Tabular
	E-MTAB-5761-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-5761-configuration.xml	Xml
	E-MTAB-5761-percentile-ranks.tsv	Tabular
	E-MTAB-5761.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 51

Similar Datasets

Gene expression profiling of peripheral blood mononuclear cells (PBMCs) 8 hours after exposure to 1 Gy of carbon or iron ions

Project description:Under certain circumstances, humans can be exposed to ionizing radiation from heavy ions. Examples are cancer patients undergoing particle therapy (e.g. carbon ions) or astronauts in deep Space missions (iron ions which contribute for a large fraction to the possible health effects of cosmic radiation because of their high ionisation power). Understanding the differences in the cellular response to low- and high-LET radiation is important in order to adequately model risk estimates based on extrapolations from low-LET exposures. To address this need, we compared the transcriptional profiles of freshly isolated peripheral blood mononuclear cells after exposure to 1 Gy of X-rays, iron ions or carbon ions. Data of X-ray exposure have been submitted in E-MTAB-3463: https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-3463/.

2018-02-21 | E-MTAB-5761 | biostudies-arrayexpress

E-MTAB-4748

Project description:RNA-seq of coding RNA in human fibroblasts, Peripheral Blood Mononuclear Cells (PBMCs) and induced pluripotent stem cells (iPS cells) as part of the HipSci project

2025-01-23 | E-MTAB-4748 | ExpressionAtlas

Gene expression in circulating mononuclear cells after exposure to ultrafine carbon particles

Project description:Peripheral blood samples were collected before (0 hour) and at 24 hours after exposure from healthy subjects who participated in previous controlled exposures to ultrafine carbon particles (UFP, 50 microg/m3) or filtered air (FA)(n = 3 each). The exposure time was 2 hours. RNA from mononuclear cell fraction (>85% lymphocytes) was extracted, amplified and hybridized to Affymetrix HU133 plus 2 microarrays. We used microarray to explore significantly altered genes after ultrafine carbon particle exposure. Each subject was exposed to filtered air or ultrafine carbon particles. Two peripheral blood samples (pre- and post-exposure) were taken. Mononuclear cells were isolated for gene expression analysis.

2010-06-29 | E-GEOD-19317 | biostudies-arrayexpress

E-MTAB-9808

Project description:RNA-seq of porcine peripheral blood mononuclear cells treated with lipopolysaccharide and dexamethasone

2020-12-09 | E-MTAB-9808 | ExpressionAtlas

Gene expression in circulating mononuclear cells after exposure to ultrafine carbon particles

2010-06-30 | GSE19317 | GEO

Sen2020 - Metabolic alteration in PBMCs associated with type 1 diabetes

Project description:Genome-Scale draft model for Human Peripheral Blood Mononuclear Cells (PBMCs). A GEM for PBMCs was developed by applying the INIT algorithm on Human Metabolic Reconstruction (HMR 2.0) as a template model. GEMs were contextualised/ constrained for different conditions using expression datasets. The gene/transcript expression data obtained from PBMCs of Type 1 Diabetes progressors, non-progressors, and healthy controls were employed to score each reaction of HMR 2.0. For further detail please refer to Electronic Supplementary Information of Sen et.al, Metabolic alterations in immune cells associate with progression to type 1 diabetes, Diabetologia, 15/01/2020, (https://doi.org/10.1007/s00125-020-05107-6).

2020-03-11 | MODEL1905270001 | BioModels

Phosphoproteomics in LRRK2 mutation carriers

Project description:To investigate differential protein and phospho-protein changes in the signaling cascades related to mutant G2019S LRRK2 using peripheral blood mononuclear cells (PBMCs)

2022-09-07 | PXD028221 | JPOST Repository

E-GEOD-68548

Project description:The gene expression profile of peripheral blood mononuclear cells (PBMCs) of infants (6 to 11 months) immunized with an inactivated EV71 vaccine or placebo

2025-01-24 | E-GEOD-68548 | ExpressionAtlas

Exposure of PBMCs to SARS-CoV-2, as opposed to SARS-CoV, induces cell-intrinsic type I innate immunity responses in several immune cell types in the absence of productive infection

Project description:We investigate the response of peripheral blood mononuclear cells (PBMCs) to SARS-CoV and SARS-CoV-2 exposure.

2022-03-04 | GSE197665 | GEO

Protein expression of PBMCs treated with ITPRIPL1

Project description:Purified human ITPRIPL1-extracellular domain (ITPRIPL1-ECD) protein or PBS was added to human peripheral blood mononuclear cells (PBMCs) as a widely used source of immune cells and treated for 18 hours under 37℃, 5% CO2 in separate 1.5 ml EP tubes (n=3 independent samples for each condition)

2024-03-10 | PXD050518 |

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data